السلامة الدوائية و الفاعلية العلاجية لمستحضر البروبولس لعلاج الإصابة التجريبية لالتهاب الضرع في النعاج

Other Title(s)

Pharmacological safety and therapeutic efficacy of propolis preparation in experimental mastitis of ewes

Joint Authors

حيدر فلاح حسن
دريد عبد الهادي عباس
الجبوري، كفاح عودة سلمان

Source

المجلة العراقية للعلوم البيطرية

Publisher

University of Mosul College of Veterinary Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

73

Main Subjects

Zoology
Veterinary Medicine

Topics

• Udder inflammation
• Therapeutics
• Propolis
• Staphylococcus
• Ewes

English Abstract

This study for the evaluation safety o f uses propolis at (1%, 2.5%, 5%, 10%) concentrations (alone and synergistically with antibiotic) inside the intramammary the lactation period of the healthy ewes, compar ed with treated and control groups.

The result of safety test indicated that the uses of propolis as intramammary infusion inside the teat cause some e ffects that disappeared later, like elevation of SCC in milk, decre ase in milk yield, prolong residue time for propolis, in addition to the hardness in the consistency of the udder and enlargement the supramammay lymph node when compared with treated and control groups.

Also there is significant diffe rence between groups in milk composition.

The second trial was to evaluate the Pharmacological activity of propolis preparation and synergism preparation and compared it with antibiotic and control groups in treatment of experimentally induced Staphylococcus aureus Mastitis in the udder of ewes, a fter confirmed the diagnosis of Staphylococcus aureus strains by Api 20 Staph, one isolate of Staphylococcus aureus was selected based on (its resistance to 10 of 12 antibiotic tested).

The infected dose 5 cfu/ml of bacterial suspension was selected to experimentally induced Staphylococcus aureus mastitis in 25 ewes, After the appearance o f infe ction 18 -72 hours post inoculation of bacterial suspension of Staphylococcus aureus in the udder by intramammary route in ewes, the ewes treated para enterally by antibiotic, antiinflammatory and antipyretic drug and locally in four groups (propolis 1% and 10%) (8 ewes) which appeared very mild side effe cts, synergism between propolis and antibiotic (4 ewes), antibiotic (12 ewes) and (1 ewe) as control group.

The r esults showed systemic cure in all ewes but with differences in the local clinical cure between groups according to the type of antibiotic and its company production without bacterial cure in all groups , so that make the ewes under the risk of reinfection under any stress condition

Data Type

Conference Papers

Record ID

BIM-831001

• APA
• MLA
• AMA