Antimicrobial and antioxidant activities of a series of aromatic nitrones

Other Title(s)

Activité antimicrobienne et antioxydante d’une série de nitrones aromatique

Joint Authors

Meklat, Atika
Touati, Abd al-Qadir
Ayt Yahya, Ahmad
Baltas, Michel
Sad, Mawlay
Bouras, Nur al-Din

Source

Algerian Journal of Arid Environment

Issue

Vol. 7, Issue 2 (31 Dec. 2017), pp.27-36, 10 p.

Publisher

Université Kasdi Merbah Ouargla Faculté des sciences de la nature et de la vie Laboratoire de protection des écosystèmes en zones arides et semi-arides

Publication Date

2017-12-31

Country of Publication

Algeria

No. of Pages

10

Main Subjects

Natural & Life Sciences (Multidisciplinary)

Abstract EN

Microbiological tests of a series of nitrones were performed by measuring the minimum inhibitory concentration (MIC) on sixteen targeted microorganisms.

The results obtained showed that these compounds exhibited good antimicrobial activity and that this activity was dependent on the substituent on the aryl group of the nitrone.

The addition of a surfactant was found to enhance this activity.

In addition, the antioxidant activity tests of these nitrones was assessed using three chemical tests: 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical, β-carotene bleaching, and "ferric reducing antioxidant power" (FRAP) method.

The tests showed that these compounds exhibited an antioxidant capacity similar or better than α-phenyl-N-tert-butylnitrone (PBN) which was used as a reference.

Abstract FRE

Des tests microbiologiques d’une série de nitrones sont effectués.

Les résultats obtenus montrent que les composés présentent une bonne activité antimicrobienne et que cette activité est sensible à la substitution.

Aussi, l’addition de surfactant a amélioré cette activité.

Les résultats sont affinés par la mesure de la CMI sur seize microorganismes cibles.

De même, des tests d’activité antioxydant des nitrones en utilisant trois tests chimiques: la méthode de DPPH «1,1-dipheny1-2 picrylhydrazule», la méthode de blanchissement de β carotène et la méthode FRAP «ferric réducing antioxydant» sont réalisés.

Ces tests montrent que les composés présentent un pouvoir antioxydant similaire ou meilleur à celui de la nitrone de référence l’α-phényl-N-tertbutylnitrone (PBN).

American Psychological Association (APA)

Hamzah, Kahina& Touati, Abd al-Qadir& Meklat, Atika& Ayt Yahya, Ahmad& Bouras, Nur al-Din& Baltas, Michel…[et al.]. 2017. Antimicrobial and antioxidant activities of a series of aromatic nitrones. Algerian Journal of Arid Environment،Vol. 7, no. 2, pp.27-36.
https://search.emarefa.net/detail/BIM-834295

Modern Language Association (MLA)

Hamzah, Kahina…[et al.]. Antimicrobial and antioxidant activities of a series of aromatic nitrones. Algerian Journal of Arid Environment Vol. 7, no. 2 (Dec. 2017), pp.27-36.
https://search.emarefa.net/detail/BIM-834295

American Medical Association (AMA)

Hamzah, Kahina& Touati, Abd al-Qadir& Meklat, Atika& Ayt Yahya, Ahmad& Bouras, Nur al-Din& Baltas, Michel…[et al.]. Antimicrobial and antioxidant activities of a series of aromatic nitrones. Algerian Journal of Arid Environment. 2017. Vol. 7, no. 2, pp.27-36.
https://search.emarefa.net/detail/BIM-834295

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 34-36

Record ID

BIM-834295