Predictability of the Expression of ER, PR Receptors, HER2 and AgNORs in Breast carcinoma among Iraqi women in Thi-Qar Province : immunohistochemical study

Abstract EN

This study is descriptive exploratory in Thi – Qar providence for some breast cancer patients .The study aims of the study to assess the relationship between ER,PR,HER2 and the nuclear regulatory regions Argyrophilic nucleolar organizer region (AgNOR( in breast cancer.

The present study addressed the identification the nuclear organization region in the breast cancer patients in Thi- Qar providence and the extent of their association with ER, PR and HER2 in the occurrence of breast cancer.

Fifty tissue samples collected from Hussein Teaching Hospital in Thi Qar and some private laboratories in the province with the province of each case data included the most important factor is age, found that the highest percentage of injuries, age (55-46 years) increased by 38%.

And mixed samples.

Either partial removal of the tumor or whole breast.

The results of the current study showed that there was a clear positive relationship between nuclear organization regions and breast cancer, as it was noted the presence of many of the nuclear regions of the dye-derived tissue sections of tumors while nuclear chromosomal regions did not appear in the sections derived from tumors with negative expression of estrogen receptor and progesterone hormone.