Association between amblyopia and fundus ischemic changes

Abstract EN

This study was done in Al- Diwaniah city in Iraq, extended from January 2015-April 2017 and involved 80 patients, among them number of females was higher than males (51 and 29 respectively) and their age range between 45-70 years.

Data for the study was collected from the patients attending ophthalmological department in the hospital, out patients and private clinic either for regular checking or sent by their physician to be examined for the presence of ophthalmologic complications, (62) patients among them have combined hypertension and diabetes, (4) patients having only diabetes millets, (13) have DM, hypertension and hyperlipidemia and only one have just hypertension, this selected group all have amblyopia unilateral or bilateral; their visual acuities varied from mild to severe and their amblyopia caused by wide ranges of causes mainly refractive error, fundoscopic examination was done to see the association between amblyopia and fundal ischemic changes; the amblyopic eye have delayed awareness regarding ischemia and this affect fundus findings, this idea can be used in future to protect the eye from ischemia by delaying its response to neurological signals that incite cascade of ischemia by using a neuroprotective agents which act on GABArgic neurotransmitters and affect ischemic cascade .