مقارنة بين محلول رنجر لاكتات و محلول هيدروكسي-ايتيل ستارتش منخفض الوزن الجزيئي (HES 1300.4)‎ للاستخدام في دارة القلب و الرئة الاصطناعية

Abstract EN

Background& Objective: the type of prime solution is essential in the prognostis in cardiac surgery and the ideal solution is still a topic of much debate.

Aim: comparison between Ringer Lactate and HES 130/0.4 as prime solution on the renal function, hemostasis, postoperative drainage and transfusion.

Materials & Methods: prospective randomized study included 26 patients undergoing on-pump CABG, received 1500 ml Ringer Lactate or 1500 ml (HES 130/0.4) as prime solution, many markers : Hco3, Lactate, ions, Urea, Createnine, Hg, Ht, Platelets, INR, postoperative drainage and blood –FFP transfusion were measured before induction T1 to second day after surgery T4.

Results: no significant difference between groups on renal function and ionic balance, and no difference on the amount of drainage, blood and FFP transfusion, another result of this study was that (HES 130/0.4) did not have negative effect on renal function and hemostasis.

Conclusion: we can use (HES 130/0.4) as an alternative solution in place of Ringer Lactate solution in cardiopulmonary bypass.