دراسة سريرية و تشريحية مرضية ل 185 آفة مصطبغة في مستشفى الأمراض الجلدية و الزهرية-جامعة دمشق

Abstract EN

Objective: Determining the correlation between initial clinical and his to pathological diagnosis.

Materials and Methods: A clinicopathological study of 185 pigmented skin lesions was conducded in the hospital of dermatology and Venereology at Damascus University.

We evaluate the correlation between clinical and his to pathological diagnosis, and relate the result with age and sex.

Results: The lesions examined included 130 melanocytic lesions (118 benign nevi, 7 dysplastic nevi, 5 cases of cutaneous malignant melanoma), and 55 nonmelanocytic lesions (12 pigmented basal cell carcinoma, 13 seborrheic keratosis and 30 different benign lesions).

The average age of most patients was 40-60 years, with a male to female ratio of 1:1.3.

The Majority of lesions were located on the head and neck region.

Analysis of clinical diagnosis with histopathological diagnosis revealed a positive correlation of 78.3% and negative correlation of 21.6%.

Seborrheic keratosis and basal cell carcinoma were the most common nonmelanocytic lesions to be misdiagnosed as malignant melanoma clinically.

There was lack of clinicopathological correlation in dysplastic naevus.

Conclusions: Pigmented lesions include both melanocytic as well as nonmelanocytic lesions.

A considerable or sufficient correlation between clinical diagnosis, dermoscope, biopsy and histopathological diagnosis is necessary for the accurate diagnosis and definite treatment of patients with pigmented skin lesions