الحماض الخلوني السكري : مقارنة بين حقبتين : دراسة مقطعية مستعرضة في مستشفى الأسد الجامعي-دمشق

Abstract EN

Background &Objective: The aim of this study was to compare precipitating factors and outcomes of diabetic ketoacidosis (DKA) between two periods (1992 -1997) and (2006 - 2012) at Al-Assad University Hospital.

Methods & Materials: This is a cross sectional retrospective study.

A comprehensive review was conducted on medical records of patients who were admitted from January 2006 to December 2012 under the impression of DKA.

Precipitating factors and outcomes were identified.

Then data were compared with the results of an old study on DKA at the same hospital on DKA records between 1992 and 1997.

All included episodes fulfilled the American Diabetic Association DKA diagnostic criteria.

Results: In comparison of DKA between 2006-2012 period (114 episode) and 1992-1997 period (100 episode) precipitating factors order was similar (infection, therapy problems, then other factors) with different but insignificant percentages.

Mortality rate was apparently increased from 5% to 11.3%.

The severity of underlying precipitating illness, along with aging were risk factors that affected mortality rate.

Conclusions: There was no significant difference between the two periods regarding DKA precipitating factors and outcomes.