Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid
Joint Authors
Miao, Mingsan
Liu, Baosong
Peng, Mengfan
Bai, Ming
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 3 (31 Mar. 2019), pp.577-581, 5 p.
Publisher
Publication Date
2019-03-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Objective: Observe anti-inflammatory effect and the effect on acute pharyngitis rats model induced by ammonia water of compound Lobelia oral liquid, providing experimental basis for its clinical use.
Methods: Use egg white establish foot swelling rats model and use carboxymethyl cellulose establish white blood cell migration rats model.
Then observe the anti-inflammatory effect of compound Lobelia oral liquid.
Use 15% ammonia spray at pharyngeal establish acute pharyngitis rats model, Visual observation and conduct grading of pharyngeal tissue stimulation in rats, measure the levels of TNF-a and IL-6 in serum.
Pharyngeal tissue was taken to observe the morphological changes.
Result: All dose groups of compound Lobelia oral liquid can reduce the rate of foot swelling of rats at all time points (P < 0.01 or P < 0.05), and significantly reduce the number of white blood cells of rats (P < 0.01); And improve the local hyperemia degree, reduce secretion, reduce local swelling of pharyngeal tissue, reduce the serum TNF-a and IL-6 levels of acute pharyngitis rats with different degrees (P < 0.01 or P < 0.05).
Conclusion: Compound Lobelia oral liquid has a good anti-inflammatory effect on foot swelling and white blood cell migration rats model, as well as significant improvement effect on acute pharyngitis rats model.
American Psychological Association (APA)
Liu, Baosong& Bai, Ming& Peng, Mengfan& Miao, Mingsan. 2019. Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid. Saudi Journal of Biological Sciences،Vol. 26, no. 3, pp.577-581.
https://search.emarefa.net/detail/BIM-887240
Modern Language Association (MLA)
Liu, Baosong…[et al.]. Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid. Saudi Journal of Biological Sciences Vol. 26, no. 3 (Mar. 2019), pp.577-581.
https://search.emarefa.net/detail/BIM-887240
American Medical Association (AMA)
Liu, Baosong& Bai, Ming& Peng, Mengfan& Miao, Mingsan. Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 3, pp.577-581.
https://search.emarefa.net/detail/BIM-887240
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 581
Record ID
BIM-887240