Association between PDE4D polymorphism and ischemic stroke in young population

Joint Authors

Zhang, Ping
Liu, Lixia
Yue, Xuejing
Yan, Haiqing
Gui, Yongkun
Song, Jinggui

Source

Saudi Journal of Biological Sciences

Issue

Vol. 26, Issue 5 (31 Jul. 2019), pp.1023-1026, 4 p.

Publisher

Saudi Biological Society

Publication Date

2019-07-31

Country of Publication

Saudi Arabia

No. of Pages

4

Main Topic

Biology

Topics

Abstract EN

Objective: To explore the association between the polymorphisms of the phosphodiesterase (PDE) 4D gene (SNP83 and SNP87) and the risk of ischemic stroke (IS) in Chinese young population.

Methods: This study included 393 patients who were divided into IS group and non-IS group.

Semiconductor high-throughput sequencing technology and multivariate logistic regression analysis were performed.

Results: In the case group, the frequency of CC genotype and C allele of the SNP83 gene was significantly higher than that in the control group.

There was no significant difference in genotype frequency distribution of SNP87 between the two groups.

Conclusion: We found an association between SNP83 and the risk of IS in Chinese young population from northern Henan province.

There was not a significant association between SNP87 and IS in Chinese young population.

American Psychological Association (APA)

Yue, Xuejing& Liu, Lixia& Yan, Haiqing& Zhang, Ping& Gui, Yongkun& Song, Jinggui. 2019. Association between PDE4D polymorphism and ischemic stroke in young population. Saudi Journal of Biological Sciences،Vol. 26, no. 5, pp.1023-1026.
https://search.emarefa.net/detail/BIM-891137

Modern Language Association (MLA)

Zhang, Ping…[et al.]. Association between PDE4D polymorphism and ischemic stroke in young population. Saudi Journal of Biological Sciences Vol. 26, no. 5 (Jul. 2019), pp.1023-1026.
https://search.emarefa.net/detail/BIM-891137

American Medical Association (AMA)

Yue, Xuejing& Liu, Lixia& Yan, Haiqing& Zhang, Ping& Gui, Yongkun& Song, Jinggui. Association between PDE4D polymorphism and ischemic stroke in young population. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 5, pp.1023-1026.
https://search.emarefa.net/detail/BIM-891137

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 1026

Record ID

BIM-891137