Taxonomy and antimicrobial activity of streptosporangium strain SG163 isolated from a Saharan soil

Abstract EN

In a continuing search for new antimicrobial products from actinobacteria collected in Algerian Saharan soils, an isolate of actinobacteria, designated Sg163, was selected for its interesting antimicrobial activity.

The isolate was identified to the genus Streptosporangium by phenotypic and molecular criteria.

The cultural and physiological characterizations as well as phylogenetic analysis indicated that the isolate was different from known members of the genus Streptosporangium.

Analysis of the 16S rRNA sequence showed 97.09 to 98.27 % similarity with those of Streptosporangium type strains.

The strain Sg163 produced antifungal and antibacterial activities on several culture media.

The highest antimicrobial activities were obtained in ISP2 medium.

Three active products C1, C2 and C3 with both antifungal and antibacterial activities were isolated and purified by chromatographic methods with C2, as the major compound.

The data of the infrared spectroscopy and the chemical revelations, suggested that the active molecules were glycosylated aromatic compounds.