دراسة راجعة عن خمج جراثيم الملوية البوابية في مستشفى الأطفال الجامعي بدمشق

Abstract EN

Objective: Helicobacter pylori (H.

pylori) is recognized as the most common chronic human bacterial infection, affecting up to 50% of the world’s population, and plays an important role in promoting gastrointestinal disease and extra-gastrointestinal disease in human.

Infection is usually acquired in childhood, particularly in developing countries.

In this study, we will show the prevalence of H.

pylori infection in children with gastrointestinal and nongastrointestinal symptoms, and the association between H.

pylori infection and clinical manifestations in children in the University Children's Hospital in Damascus.

Methods: The study was conducted at the University Children’s Hospital in Damascus between 2015 and 2016, which is a cohort study based on the files of patients who were referred to the hospital with gastrointestinal and extra-gastrointestinal symptoms (chronic abdominal pain, upper gastric hemorrhage, chronic vomiting, iron deficiency anemia or growth failure).

They have gastrointestinal endoscopy, gastric biopsy, and were diagnosed with H.

pylori infection without exception any patient.

Data on patients (age, sex, family history, gastrointestinal endoscopy, and gastric biopsy) were collected, the information was arranged in tables and ratios using the SSPS program.

Results: Of the 630 patients who underwent gastrointestinal endoscopy and biopsies, 89 patients were diagnosed with infection (14.1% of the total number of patients), of them 67.46% were older than 10 years (60 patients), males 58.4% (n=52), females 41.6% (n=37), the most common symptom in patients was chronic abdominal pain in 37 patients (41.5%).

The most common endoscopic finding was nodular hyperplasia in 35 patients (39.3%).

The most common pathologic findings was active moderate gastritis (28 patients, 31.4%).

Conclusions: There is a high incidence of hepatitis infection in children and even in young age less than 10 years, and should be investigated for infection in any patient with symptoms of digestive and external digestive suggestive, especially chronic abdominal pain.

However; existence of antral nodularity can be assigned as an endoscopic sign of infection in children.