Tumour necrosis factor-α (TNF-α) in mycotic aborted placenta : an evaluation by Immunohistochemistry
Other Title(s)
تقييم (a-TNF) في المشيمة المجهضة بسبب الإصابات الفطرية بواسطة الكيمياء المناعية
Author
al-Tamimi, Hamid Abd al-Husayn
Source
Kufa Journal for Veterinary Medical Sciences
Issue
Vol. 10, Issue 1 (30 Jun. 2019), pp.14-24, 11 p.
Publisher
University of Kufa Faculty of Veterinary Medicine
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract EN
the present study aims to study histopathological changes in the mycotic aborted and normal placenta of sheep ,in addition to study the levels of TNF-a in mycotic aborted and normal placenta by immunohistochimistry assay (IHC) Seventy five , samples of aborted placenta and twenty five of normal placenta were collected , during November 2017 to May 2018 from certain regions of AL-Najaf city .
Placental samples were fixed in 10% neutral buffer formalin for 72 hrs for histopathological examination, paraffin embedded tissue belong to mycotic aborted and normal group were used for assessment of TNF alpha by immmunohistopathological study was carried out to determine TNF protein in the placenta sample.
Histopathological examination showed suppurative necrotized placentitis, in addition to congestion of the blood vessels and fibrin deposition in the intera-villius space as well as calcium deposition in necrotized the necrotic area and fibrosis of stromal area in certain chorionic villi and sloughing and desquamation of syncytotrophoblast.
Result of IHC of TNF alpha protein showed significant elevation in TNF alpha protein in inflammatory cell (macrophage) of aborted sheep placenta (increasing of intensity and score), while no changes could be observed for pro-inflammatory molecules in the control sample (normal delivery).
American Psychological Association (APA)
al-Tamimi, Hamid Abd al-Husayn. 2019. Tumour necrosis factor-α (TNF-α) in mycotic aborted placenta : an evaluation by Immunohistochemistry. Kufa Journal for Veterinary Medical Sciences،Vol. 10, no. 1, pp.14-24.
https://search.emarefa.net/detail/BIM-895900
Modern Language Association (MLA)
al-Tamimi, Hamid Abd al-Husayn. Tumour necrosis factor-α (TNF-α) in mycotic aborted placenta : an evaluation by Immunohistochemistry. Kufa Journal for Veterinary Medical Sciences Vol. 10, no. 1 (2019), pp.14-24.
https://search.emarefa.net/detail/BIM-895900
American Medical Association (AMA)
al-Tamimi, Hamid Abd al-Husayn. Tumour necrosis factor-α (TNF-α) in mycotic aborted placenta : an evaluation by Immunohistochemistry. Kufa Journal for Veterinary Medical Sciences. 2019. Vol. 10, no. 1, pp.14-24.
https://search.emarefa.net/detail/BIM-895900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 24
Record ID
BIM-895900