Determination of the role of t-helper 17 and 22 vs T-reg cells in patients with molluscum contagiosum
Author
Source
al-Kufa University Journal for Biology
Issue
Vol. 10, Issue 3 (31 Dec. 2018), pp.15-26, 12 p.
Publisher
University of Kufa Faculty of Science Department of live Sciences
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
Molluscum contagiosum is skin disease and well known by dermatologists, the causative agent is a pox virus.
Infection, usually self limited within few months in individuals with a normal health and immune system.
From 205 case females recorded 95(46.3%) and 110(53.7%) males.
The results showed that there were a highly significant increment in concentration of IL 17A (132.66 ± 24.7pg/ml) compared with control group which was (42.59±13.4pg/ml).
Results also showed that there is highly significant increment in concentrations of IL 23P19 (112.33 ±17pg/ml) compared with control group which was (21.11±9.6pg/ml).
Also documented data declared a highly significant increment in concentrations of IL 22 (77.11±8.8pg/ml) in comparison to control group which was (18.11±12pg/ml).
The relative expression of the gene FoxP3 gene showed increment in patients group (17.723 ± 1.227) compared with control group which was (2.133±1.234), results of NFAT gene showed increment in patients group (13.676±2.223) compared with control group which was (2.743±1.133) and result of AP1gene showed increment in patients group (3.7883±1.234) compared with control group which was (1.8766±0.889).
These findings indicate the potent immune response against the virus infection which belongs to Th 17 and 22 and the controlling mechanisms through the regulatory T cells which maintain the response in the normal levels.
American Psychological Association (APA)
al-Khuzai, Ziyad M. F.. 2018. Determination of the role of t-helper 17 and 22 vs T-reg cells in patients with molluscum contagiosum. al-Kufa University Journal for Biology،Vol. 10, no. 3, pp.15-26.
https://search.emarefa.net/detail/BIM-899092
Modern Language Association (MLA)
al-Khuzai, Ziyad M. F.. Determination of the role of t-helper 17 and 22 vs T-reg cells in patients with molluscum contagiosum. al-Kufa University Journal for Biology Vol. 10, no. 3 (2018), pp.15-26.
https://search.emarefa.net/detail/BIM-899092
American Medical Association (AMA)
al-Khuzai, Ziyad M. F.. Determination of the role of t-helper 17 and 22 vs T-reg cells in patients with molluscum contagiosum. al-Kufa University Journal for Biology. 2018. Vol. 10, no. 3, pp.15-26.
https://search.emarefa.net/detail/BIM-899092
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 23-26
Record ID
BIM-899092