Mother-daughter genetic relationship in central obesity
Joint Authors
al-Misri, Sahar A.
Khalil, Aya
Hasan, Nayrah al-Mursi
Zarruq, Wahbah Ahmad
Mira, Marwah Faruq
al-Said, Jamilah S. M.
al-Husayni, Muhammad S.
Duwaydar, Umar Husni
al-Ashmawi, Abir Atif
Source
Egyptian Pediatric Association Gazette
Issue
Vol. 66, Issue 3 (30 Sep. 2018), pp.71-77, 7 p.
Publisher
Egyptian Pediatric Association
Publication Date
2018-09-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Central obesity is an important predictor of all-cause mortality.
Children of obese parents bear a greater risk to develop obesity themselves.
Objective: To find possible correlations in central obesity and other cardio-metabolic parameters between mother and daughter.
Subjects and methods: The current study measured anthropometric, laboratory, radiologic and genetic data for 120 centrally obese mothers and their 200 daughters aged from 12 to 18 years old.
Results: Twenty-two percent of the daughters was overweight, 15.5% obese and 30% had central obesity.
Genotype E3/E4 of apolipoprotein E was the most frequent genotype in mothers group (38.3%) and daughters with visceral obesity (46.7%) while E3/E3 was the most frequent genotype in daughters group without visceral obesity (42.9%).
In both mothers and daughters, disturbed lipid profile was found in those with E3 allele, while increased BMI and weight were found among those with alleles E2 and E4 respectively.
Daughters genotype E3/E4 had the highest significant values of most of the studied anthropometric measurements and lipid profile, while mother’s genotype E4/E4 had the highest significant values of most of the studied anthropometric measurements and insulin.
Conclusion: A key role could be played by the mother in the primary prevention of central obesity due to the consistent association of central obesity indices between mothers and daughters.
American Psychological Association (APA)
al-Ashmawi, Abir Atif& Hasan, Nayrah al-Mursi& Zarruq, Wahbah Ahmad& Mira, Marwah Faruq& Khalil, Aya& al-Misri, Sahar A.…[et al.]. 2018. Mother-daughter genetic relationship in central obesity. Egyptian Pediatric Association Gazette،Vol. 66, no. 3, pp.71-77.
https://search.emarefa.net/detail/BIM-904538
Modern Language Association (MLA)
al-Ashmawi, Abir Atif…[et al.]. Mother-daughter genetic relationship in central obesity. Egyptian Pediatric Association Gazette Vol. 66, no. 3 (Sep. 2018), pp.71-77.
https://search.emarefa.net/detail/BIM-904538
American Medical Association (AMA)
al-Ashmawi, Abir Atif& Hasan, Nayrah al-Mursi& Zarruq, Wahbah Ahmad& Mira, Marwah Faruq& Khalil, Aya& al-Misri, Sahar A.…[et al.]. Mother-daughter genetic relationship in central obesity. Egyptian Pediatric Association Gazette. 2018. Vol. 66, no. 3, pp.71-77.
https://search.emarefa.net/detail/BIM-904538
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 77
Record ID
BIM-904538