O’donnell criteria as a sign of bad prognosis in hospitalized patients with bronchiectasis

Abstract EN

Objective: Bronchiectasis is an important cause of morbidity and mortality all over the world and it still a real challenge in areas that lack to healthy conditions.Determining the frequency of occurrence is particularly misleading and difficult to determine, especially in patients with multiple respiratory disorders, because it is difficult to determine the mechanism that is suspected in such cases.

The objective of this study was to evaluate the efficacy of O’Donnell criteria as a predictor of poor prognosis in hospitalized patients with acute exacerbation of bronchiectasis (AEB).

Methods: This study is observational cohort and prospective.

It was applied to patients admitted with AEB who achieved modified O’Donnell criteria and their HRCT showed bronchiectasis admitted at Aleppo University Hospital between September 2017 and January 2019.

They were divided into 5 groups by age.

Patients with bronchial asthma, COPD and cystic fibrosis were excluded.

Results: The study included 90 patients (57 males and 33 females) with a mean age of 52.93±20.437 years.

It showed a peak of incidence in age group 45-59 years.

Dyspnea is the most common symptom (94%), followed by cough (91%), while the lowest frequency was 51% for wheezing.

The average score of O’Donnell was 6.19.

Mortality rate per one year was 15.83%.

The median survival age was 13±0.214 months, a nd the mean days of hospitalization were 7.94±4.826 days.

By studying correlations between O’Donnell and variables through age groups: O’Donnell mortality association (HR 2.208; Cl: 1.353-3.604; p=0.002).

The need of long term oxygen (HR 1.381; Cl: 1.014-1.879; p=0.04).

Conclusions: O’Donnell criteria should be considered as a predictor of poor prognosis in patients with AEB and it correlates with mortality and the need of long term O2