Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae)‎ larvae infesting maize in colombia

Joint Authors

Vargas Méndez, Leonor Y.
Sanabria Flórez, Pedro L.
Saavedra Reyes, Laura M.
Merchan Arenas, Diego R.
Kouznetsov, Vladimir V.

Source

Saudi Journal of Biological Sciences

Issue

Vol. 26, Issue 7 (30 Nov. 2019), pp.1613-1620, 8 p.

Publisher

Saudi Biological Society

Publication Date

2019-11-30

Country of Publication

Saudi Arabia

No. of Pages

8

Main Subjects

Biology

Topics

Abstract EN

The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, Spodoptera frugiperda (J.E.

Smith).

Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest.

During structure–activity relationship studies and physicochemical profile analysis, it was found that among tested molecules 1–15, eugenol 1, prenyl eugenol 4, isoeugenol 8 and isoeugenol acetate 11 exhibited lethal effects LD50 at concentrations <1 mg/g of insect.

On the other hand, eugenol 1, metallyl eugenol 3, isoeugenol 8 and isoeugenol acetate 11 showed a good antifeedant activity (CE50 = 158–209 µg/mL) with a high antifeedant index (70–78%) at concentration 1000 µg/mL, possessing a weak anti-acetylcholinesterase activity (IC50 = 21–31 μg/mL).

According to their ecotoxicological profiles (LC50 = 2033.1–6303.8 µg/mL on Artemia salina larvae), isoeugenol 8 and its acetate derivative 11 could be potential used in control of the growth, feeding, or reproduction of S.

frugiperda larvae, acting as moderate insecticidal acetylcholinesterase inhibitors and/or antifeedant molecules.

Such structure–activity relationship studies could stimulate the identification of lead structures from natural sources for the development of larvicidal and deterrent products against S.

frugiperda and related insect pests.

American Psychological Association (APA)

Vargas Méndez, Leonor Y.& Sanabria Flórez, Pedro L.& Saavedra Reyes, Laura M.& Merchan Arenas, Diego R.& Kouznetsov, Vladimir V.. 2019. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284

Modern Language Association (MLA)

Vargas Méndez, Leonor Y.…[et al.]. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284

American Medical Association (AMA)

Vargas Méndez, Leonor Y.& Sanabria Flórez, Pedro L.& Saavedra Reyes, Laura M.& Merchan Arenas, Diego R.& Kouznetsov, Vladimir V.. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 1619-1620

Record ID

BIM-910284