Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia
Joint Authors
Vargas Méndez, Leonor Y.
Sanabria Flórez, Pedro L.
Saavedra Reyes, Laura M.
Merchan Arenas, Diego R.
Kouznetsov, Vladimir V.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 7 (30 Nov. 2019), pp.1613-1620, 8 p.
Publisher
Publication Date
2019-11-30
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, Spodoptera frugiperda (J.E.
Smith).
Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest.
During structure–activity relationship studies and physicochemical profile analysis, it was found that among tested molecules 1–15, eugenol 1, prenyl eugenol 4, isoeugenol 8 and isoeugenol acetate 11 exhibited lethal effects LD50 at concentrations <1 mg/g of insect.
On the other hand, eugenol 1, metallyl eugenol 3, isoeugenol 8 and isoeugenol acetate 11 showed a good antifeedant activity (CE50 = 158–209 µg/mL) with a high antifeedant index (70–78%) at concentration 1000 µg/mL, possessing a weak anti-acetylcholinesterase activity (IC50 = 21–31 μg/mL).
According to their ecotoxicological profiles (LC50 = 2033.1–6303.8 µg/mL on Artemia salina larvae), isoeugenol 8 and its acetate derivative 11 could be potential used in control of the growth, feeding, or reproduction of S.
frugiperda larvae, acting as moderate insecticidal acetylcholinesterase inhibitors and/or antifeedant molecules.
Such structure–activity relationship studies could stimulate the identification of lead structures from natural sources for the development of larvicidal and deterrent products against S.
frugiperda and related insect pests.
American Psychological Association (APA)
Vargas Méndez, Leonor Y.& Sanabria Flórez, Pedro L.& Saavedra Reyes, Laura M.& Merchan Arenas, Diego R.& Kouznetsov, Vladimir V.. 2019. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284
Modern Language Association (MLA)
Vargas Méndez, Leonor Y.…[et al.]. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284
American Medical Association (AMA)
Vargas Méndez, Leonor Y.& Sanabria Flórez, Pedro L.& Saavedra Reyes, Laura M.& Merchan Arenas, Diego R.& Kouznetsov, Vladimir V.. Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera : Noctuidae) larvae infesting maize in colombia. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1613-1620.
https://search.emarefa.net/detail/BIM-910284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1619-1620
Record ID
BIM-910284