تردد الطرز الوراثية للجين MTHFR للمصابين بتشوهات القلب الولادية في محافظة ذي قار
Other Title(s)
Frequency of genotypes of MTHFR gene for people with congenital heart defects in the Province of Thi Qar
Joint Authors
الفرطوسي، وديان كاطع
الركابي، حسن ريسان
Source
مجلة كلية التربية للعلوم الصرفة
Issue
Vol. 7, Issue 4 (31 Dec. 2017), pp.127-138, 12 p.
Publisher
University of Thi-Qar College of Education for Pure Sciences
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
The present study aimed to detect the role of MTHFR gene and their relationship in the incidence of Congenital heart defects in Dhi Qar province, through the use of PCR- RFLP technique on this basis were collected 120 blood samples (from Nasiriyah heart Center) in tubes container on EDTA from patients with congenital heart defects ages ranging between (a month - 17 years) and 110 samples from healthy people ages ranging between (a month - 17 years) and saved directly at a temperature of - 20 ° C for use in the extraction DNA and the PCR technique.
The results of the statistical analysis of the lack of correlation between polymorphism of the gene MTHFR and the incidence of congenital heart defects when compared to the comparison group And each of the mutant homogenized style(CT) (OR= 0.86 ; 95%CI= 0.41-1.81) The style of the mutant differential(TT) (OR=0.42 ; 95%CI= 0.22 - 0.79) .
The results of the current study has shown an increased risk of congenital heart defects for women who have the mutant heterozygous (CT) almost twice (OR= 1.63 ; 95%CI=0.61-4.29).
and the results also showed that who have the mutant heterozygous (CT) and within the age group (month - 9 years) has increased their risk of congenital heart defects (OR = 1.5 ; 95%CI= 0.36-6.23), results showed an increased risk of infection with parents smokers about almost three times (OR = 2.5) and the period of confidence (0.76 - 8.22) the presence of mutant homozygous (TT) while that possess the mutant heterozygous (CT) increased their risk more than injury twice (OR = 2.13) and the period of confidence (0.71 - 6.40)
American Psychological Association (APA)
الركابي، حسن ريسان والفرطوسي، وديان كاطع. 2017. تردد الطرز الوراثية للجين MTHFR للمصابين بتشوهات القلب الولادية في محافظة ذي قار. مجلة كلية التربية للعلوم الصرفة،مج. 7، ع. 4، ص ص. 127-138.
https://search.emarefa.net/detail/BIM-911535
Modern Language Association (MLA)
الركابي، حسن ريسان والفرطوسي، وديان كاطع. تردد الطرز الوراثية للجين MTHFR للمصابين بتشوهات القلب الولادية في محافظة ذي قار. مجلة كلية التربية للعلوم الصرفة مج. 7، ع. 4 (كانون الأول 2017)، ص ص. 127-138.
https://search.emarefa.net/detail/BIM-911535
American Medical Association (AMA)
الركابي، حسن ريسان والفرطوسي، وديان كاطع. تردد الطرز الوراثية للجين MTHFR للمصابين بتشوهات القلب الولادية في محافظة ذي قار. مجلة كلية التربية للعلوم الصرفة. 2017. مج. 7، ع. 4، ص ص. 127-138.
https://search.emarefa.net/detail/BIM-911535
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 135-138
Record ID
BIM-911535