العلاقة بين مستوى الببتيد الدماغي المدر للصوديوم و تراجع القطعة ST بعد إعادة التروية لدى مرضى احتشاء العضلة القلبية الحاد
Other Title(s)
Relationship between N-terminal pro brain natriuretic peptide level and ST-segment resolution after reperfusion in patients with acute myocardial infarction
Joint Authors
بساطة، وليد نديم
المشهور، قاسم المصطفى
Source
مجلة المجلس العربي للاختصاصات الصحية
Issue
Vol. 20, Issue 4 (31 Dec. 2019), pp.28-38, 11 p.
Publisher
The Arab Board of Health Specializations
Publication Date
2019-12-31
Country of Publication
Syria
No. of Pages
11
Main Subjects
Topics
Abstract EN
Objective: To investigate the association between plasma NT-proBNP levels at admission and ST-segment resolution (STR) after reperfusion in patients with ST-segment elevation myocardial infarction (STEMI).
Methods: This study included 102 patients with ST-segment elevation myocardial infarction (STEMI), who were admitted to coronary care unit at Aleppo University Heart Hospital between 1 Mars 2011 until 1 October 2011 were treated by lysis in less than 6 hours from symptoms onset, and randomly selected blood sample was taken on admission to measure plasma NT-proBNP.
Maximal ST-segment elevation was measured on the worst ECG lead before and 60-90 minutes after reperfusion.
Patients were categorized as STR(−) (<50% STR) or STR(+) (≥50% STR).
Results: Of the 102 patients included, 75 (73.5%) were STR(+).
The STR(−) group had higher median levels of NT-proBNP: 413 (59-3000) vs 79 (27-2450) pg/ml, p<0.001.
On multivariate analysis, none of the following factors including age, gender, diabetes mellitus, hypertension, smoking and infarct location had a significant association with ST-segment resolution.
only NT-proBNP level and the period between symptoms onset and therapy initiation were independent predictor factors for STR.
STR(−) patients had a higher in-hospital major cardiac events (mortality, cardiogenic shock, malignant arrhythmias) than STR(+) group, (37% vs 13%, respectively), p=0.01.
Patients with Timi flow grade (0 or 1) in coronary angiography had higher median levels of NT-proBNP: (320 vs 130 and 97) pg/ml for Timi flow grade 2 and 3, respectively.
Conclusions: We found a strong association between high levels of NT-proBNP at admission and incomplete STR in our study, suggesting that NT-proBNP may be useful to predict the prognosis in acute myocardial infarction patients at the first evaluation
American Psychological Association (APA)
بساطة، وليد نديم والمشهور، قاسم المصطفى. 2019. العلاقة بين مستوى الببتيد الدماغي المدر للصوديوم و تراجع القطعة ST بعد إعادة التروية لدى مرضى احتشاء العضلة القلبية الحاد. مجلة المجلس العربي للاختصاصات الصحية،مج. 20، ع. 4، ص ص. 28-38.
https://search.emarefa.net/detail/BIM-932626
Modern Language Association (MLA)
بساطة، وليد نديم والمشهور، قاسم المصطفى. العلاقة بين مستوى الببتيد الدماغي المدر للصوديوم و تراجع القطعة ST بعد إعادة التروية لدى مرضى احتشاء العضلة القلبية الحاد. مجلة المجلس العربي للاختصاصات الصحية مج. 20، ع. 4 (2019)، ص ص. 28-38.
https://search.emarefa.net/detail/BIM-932626
American Medical Association (AMA)
بساطة، وليد نديم والمشهور، قاسم المصطفى. العلاقة بين مستوى الببتيد الدماغي المدر للصوديوم و تراجع القطعة ST بعد إعادة التروية لدى مرضى احتشاء العضلة القلبية الحاد. مجلة المجلس العربي للاختصاصات الصحية. 2019. مج. 20، ع. 4، ص ص. 28-38.
https://search.emarefa.net/detail/BIM-932626
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 35-38
Record ID
BIM-932626