The effect of intra-abdominal carbon dioxide pressure on blood pressure in laparoscopic surgeries

Abstract EN

Backgrounds: The high intra‑abdominal carbon dioxide (CO2) gas pressure of the pneumoperitoneum may result in physiological changes.

Objectives: This study aimed to examine the impact of high CO2 pressure on intraoperative blood pressures (BPs) in patients undergoing laparoscopy surgeries.

Materials and Methods: In this quasi‑experimental clinical trial, 36 patients diagnosed with different intra‑abdominal diseases were undergone laparoscopic surgeries under a standard of CO2 pressure (≥13 mmHg).

In another group, 39 patients who were matched in age and gender were undergone laparoscopic surgeries under low CO2 pressure (≤12 mmHg).

Results: The patients in both high and low CO2 pressure groups were comparable in age (37.65 vs.

42.37 years; P = 0.114), gender (P = 0.212), and operation time (36.18 vs.

34.64 min), respectively.

The patients underwent high CO2 pressure had significantly lower levels of diastolic BP after anesthesia (72.28 vs.

77.89; P = 0.020), lowest systolic BP (SBP) (94.69 vs.

102.26; P = 0.006), and lowest diastolic BP (DBP) (59.00 vs.

68.36; P < 0.001) in contrast with higher level of postoperative diastolic BP in high CO2 group (111.23 vs.

78.11; P < 0.001).

SBP and DBP and heart rate were decreased significantly from preoperative to postanesthesia and postoperative surgery in groups.

Conclusion: The present study showed that BP parameters were deceased following laparoscopy surgeries (higher pneumoperitonial CO2 pressure has lower BP in comparison to lower pneumoperitonial CO2 pressure).

Low CO2 pressure is recommended during laparoscopic surgeries as much as possible, especially in patients with comorbidities such as heart diseases, old ages, and for operations that take longer time.