Immunohistochemistry of PPARα, PPARγ and IFNγ in kidney tissues of african catfish (clarias gariepinus) at different seasons
Joint Authors
Husayn, Muna N.
Tantawi, Aya H.
Cao, Xiaojuan
Source
Veterinary Medicine and Public Health Journal
Issue
Vol. 1, Issue 1 (31 Jan. 2020), pp.22-29, 8 p.
Publisher
Refaad Center for Studies and Research
Publication Date
2020-01-31
Country of Publication
Jordan
No. of Pages
8
Main Subjects
Topics
Abstract EN
The peroxisome proliferator-activated receptors (PPARs) and interferon γ (IFNγ) have a vital role in lipid homeostasis and immune functions respectively, and little is known about their beneficial role in kidney function during different seasons in catfish.
We used immunohistochemistry for detection of cellular expression of PPARα, PPARγ, and IFNγ in the head kidney and posterior kidney of African catfish, we found that the PPARα and PPARγ in head kidney gave a positive reaction in melanomacrophage centers (MMC), large lymphocytes, red blood cells, endothelial cells, and connective tissue capsule.
This positive reaction reached its highest at winter.
While in the posterior kidney they were detected in the cytoplasm of epithelium lining renal tubules and the summer was the highest season in expression.
However, IFNγ showed a positive reaction in the MMC and T-lymphocytes of the head kidney, which increased during the autumn season more than winter, spring and summer seasons.
While in the posterior kidney its positive reaction was found in MMC, epithelial cells lining distal convoluted tubules and few in proximal convoluted tubules.
The highest positive reaction in the posterior kidney was during the autumn season and was lowest in the summer season.
This study established an essential role for both PPARs and IFNγ in immune and excretory functions of the kidney as well as, a reverse relationship between PPARs and IFNγ in the head and posterior kidneys of catfish.
American Psychological Association (APA)
Husayn, Muna N.& Tantawi, Aya H.& Cao, Xiaojuan. 2020. Immunohistochemistry of PPARα, PPARγ and IFNγ in kidney tissues of african catfish (clarias gariepinus) at different seasons. Veterinary Medicine and Public Health Journal،Vol. 1, no. 1, pp.22-29.
https://search.emarefa.net/detail/BIM-937090
Modern Language Association (MLA)
Husayn, Muna N.…[et al.]. Immunohistochemistry of PPARα, PPARγ and IFNγ in kidney tissues of african catfish (clarias gariepinus) at different seasons. Veterinary Medicine and Public Health Journal Vol. 1, no. 1 (Jan. 2020), pp.22-29.
https://search.emarefa.net/detail/BIM-937090
American Medical Association (AMA)
Husayn, Muna N.& Tantawi, Aya H.& Cao, Xiaojuan. Immunohistochemistry of PPARα, PPARγ and IFNγ in kidney tissues of african catfish (clarias gariepinus) at different seasons. Veterinary Medicine and Public Health Journal. 2020. Vol. 1, no. 1, pp.22-29.
https://search.emarefa.net/detail/BIM-937090
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 27-29
Record ID
BIM-937090