Prostatic adenocarcinoma : age, tumor grade and level of serum prostatic antigen (PSA)
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Background: Prostate cancer is among the three most common cancers in men and among the leading cancer-related deaths worldwide.
However, the incidence in the Arab region is much lower compared to the rest of the world and ranges from 5.5% to 39.2%.
Several speculations were raised to explain the lower incidence in the Arab region including genetics causes, diet, lower testosterone levels and non-availability of PSA screening program.
Objective: To evaluate the pattern of cancer and its associations with age, tumor subtypes histological grade, PSA serum levels, and local invasion.
Design: A Retrospective Study.
Setting: Salmaniya Medical Complex, Bahrain.
Method: All histopathology reports of prostate cancer (biopsy and excision) between 1 January 2016 and 31 May 2018 were included in the study.
The clinical information and histopathological reports were collected and analyzed by SPSS, 20th edition.
Result: Forty-two prostate cancers were diagnosed from 1 January 2016 to 31 May 2018.
The mean age at diagnosis was 69.69 years.
The disease was bilateral in 18 (43%) patients, unilateral in 9 (21%) patients and unspecified in 15 (36%) patients.
The Gleason score of 7 was the most frequent score detected in 17 (41%) patients.
The Gleason score was higher in the age group between 85-90 years and in those who had PSA serum levels > 100 ng/ml.
Conclusion: Prostate cancer is one of the most common cancers in Bahraini males, especially those above 65 years.
The severity of the disease increases with age and PSA serum levels above the normal range.
This highlights the importance of early detection by screening program targeting men in the age group 50-75 years.
American Psychological Association (APA)
Jad Allah, Asma Salah& al-Hashimi, Fatimah. 2020. Prostatic adenocarcinoma : age, tumor grade and level of serum prostatic antigen (PSA). Bahrain Medical Bulletin،Vol. 42, no. 2, pp.104-106.
Modern Language Association (MLA)
Jad Allah, Asma Salah& al-Hashimi, Fatimah. Prostatic adenocarcinoma : age, tumor grade and level of serum prostatic antigen (PSA). Bahrain Medical Bulletin Vol. 42, no. 2 (Jun. 2020), pp.104-106.
American Medical Association (AMA)
Jad Allah, Asma Salah& al-Hashimi, Fatimah. Prostatic adenocarcinoma : age, tumor grade and level of serum prostatic antigen (PSA). Bahrain Medical Bulletin. 2020. Vol. 42, no. 2, pp.104-106.
Includes bibliographical references : p. 106
Arab Citation & Impact Factor "Arcif"
Largest Arabic Database of Citations Analysis for the Arabic Scholarly Journals Issued in Arab World.