Von Willebrand Disease : the diagnosis and management of this bleeding disorder
Joint Authors
al-Salihi, Nawras J.
Abd, Basim A.
Source
Issue
Vol. 17, Issue 2 (30 Jun. 2020), pp.122-125, 4 p.
Publisher
University of Babylon College of Medicine
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Topics
Abstract EN
von Willebrand disease (vWD) is one of the most common bleeding disorders, first described by Erik von Willebrand in the Aland Islands.
It occurs as a result of decreased or abnormal von Willebrand factor (vWF), a factor that is needed in the process of blood coagulation ; acting like a “glue” helping platelets to stick together and form the blood clot.
The principal function of vWF is binding with other clotting factors (especially Factor VIII) that are also necessary in the clotting process.
There are two main forms of this disease: the inherited and the acquired forms; each one’s pathophysiology depends on the qualitative or the quantitative defects in vWF.
The diagnosis of vWD depends on several factors : measurement of vWD antigen, vWF activity assay, the activity of Factor VIII, and some other additional tests.
The management of this disease includes replacement therapy, nonreplacement therapy, and some other kinds of managements that include the use of fibrinolytics and topical agents.
American Psychological Association (APA)
Abd, Basim A.& al-Salihi, Nawras J.. 2020. Von Willebrand Disease : the diagnosis and management of this bleeding disorder. Medical Journal of Babylon،Vol. 17, no. 2, pp.122-125.
https://search.emarefa.net/detail/BIM-972602
Modern Language Association (MLA)
Abd, Basim A.& al-Salihi, Nawras J.. Von Willebrand Disease : the diagnosis and management of this bleeding disorder. Medical Journal of Babylon Vol. 17, no. 2 (Jun. 2020), pp.122-125.
https://search.emarefa.net/detail/BIM-972602
American Medical Association (AMA)
Abd, Basim A.& al-Salihi, Nawras J.. Von Willebrand Disease : the diagnosis and management of this bleeding disorder. Medical Journal of Babylon. 2020. Vol. 17, no. 2, pp.122-125.
https://search.emarefa.net/detail/BIM-972602
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 124-125
Record ID
BIM-972602