Evaluation of serum 1, 5-anhydroglucitol levels among type 2 diabetic patients in Basrah

Abstract EN

Objective : To determine serum 1, 5- anhydroglucitol (1, 5-AG) levels among patients with type 2 diabetes (T2D) in Basrah, and to evaluate the changes in 1, 5-AG levels with regard to the status of glycaemic control.

Methods: The present study included 76 patients with T2D, 33 males and 43 females, 30-78 years of age.

Height, weight, waist circumference, systolic blood pressure, and diastolic blood pressure were measured.

Fasting blood glucose (FBG), glycated haemoglobin (HbA1c) and serum 1, 5-AG levels were determined.

Results: The study revealed that T2D patients have low serum 1, 5-AG concentrations (3.62 ±1.56) µg/ml.

The comparative male and female values were (3.69±1.55) µg/ml and (3.57±1.58) µg/ml.

The vast majority of the included diabetic patients (90.8% ) were in a state of poor glycemic control, with 6.6% have an sub-optimal metabolic control.

On the other hand, good glycemic was documented in 2.6 % of patients.

There were no significant differences in plasma 1, 5-AG concentrations with regard to the status of glycaemic control (P > 0.05).

Conclusion: T2D patients have reduced serum 1, 5-AG concentrations.

Thus, it could be, potentially, valuable test for the diagnosis of diabetes mellitus.

Diabetic patients were in poor glycaemic state.

Therefore, they are at a substantial risk for the development of diverse diabetic complications.