Predictors of functional outcome after treatment of acute ischemic stroke
Joint Authors
Abd al-Munim, Imad F.
Afifi, Fathi M.
Ismat, Ahmad
Source
Suez Canal University Medical Journal
Issue
Vol. 23, Issue 2 (31 Dec. 2020), pp.176-181, 6 p.
Publisher
Suez Canal University Faculty of Medicine
Publication Date
2020-12-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background: Acute ischemic stroke (AIS) is a common condition with significant consequences.
Advances in treatment modified outcome and prognosis.
Aim: The present study aimed to discuss the predictors of functional outcome of AIS after the first three months.
Patients and Methods: All the studied 131 patients had careful history taking, thorough clinical examination, and noncontrast brain CT scans.
The initial severity of the stroke and evolution after thrombolysis was evaluated using the National Instituted of Health Stroke Scale (NIHSS).
Patients were treated with low molecular weight heparin (LMWH) orrt-PA.
Functional status atthree months was evaluated using the modified Rankin Scale.
Results: The present study included 131 patients with AIS.
Favorable functional outcome was achieved in 52 patients (39.7 %) while the remainder 79 patients had a poor outcome.
Using logistic regression analysis, significant predictors of poor outcome on univariate analysis included age ≥ 60 years (OR:3.2, CI: 1.3-7.9,p=0.014), presence of atheromatous plaques (OR: 16.8, CI: 4.8-58.3, p< 0.001), late initiation of treatment (OR: 10.6, CI: 3.4- 32.1,p< 0.001) and persistent occlusion (OR: 7.8, CI: 3.2-18.8, p< 0.001).
However, on multivariate analysis, variable predictive of poor outcome included age ≥ 60 years (OR: 32.5, CI: 5.4-196.5, p < 0.001), presence of atheromatous plaques (OR: 9.4, CI: 1.7-51.2, p= 0.01), late initiation of treatment (OR: 10.0, CI: 1.5-67.1,p= 0.018) and persistent occlusion (OR:25.7, CI: 6.9-95.8,p < 0.001).
Conclusions: Independent predictors of poor outcome in AIS patients include age ≥ 60 years, presence of atheromatous plaques, late initiation of treatment, and persistent occlusion
American Psychological Association (APA)
Abd al-Munim, Imad F.& Afifi, Fathi M.& Ismat, Ahmad. 2020. Predictors of functional outcome after treatment of acute ischemic stroke. Suez Canal University Medical Journal،Vol. 23, no. 2, pp.176-181.
https://search.emarefa.net/detail/BIM-980527
Modern Language Association (MLA)
Abd al-Munim, Imad F.…[et al.]. Predictors of functional outcome after treatment of acute ischemic stroke. Suez Canal University Medical Journal Vol. 23, no. 2 (2020), pp.176-181.
https://search.emarefa.net/detail/BIM-980527
American Medical Association (AMA)
Abd al-Munim, Imad F.& Afifi, Fathi M.& Ismat, Ahmad. Predictors of functional outcome after treatment of acute ischemic stroke. Suez Canal University Medical Journal. 2020. Vol. 23, no. 2, pp.176-181.
https://search.emarefa.net/detail/BIM-980527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 180-181
Record ID
BIM-980527