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Six Years Follow-up of the Levels of TNF-α and IL-6 in Patients with Complex Regional Pain Syndrome Type 1
Joint Authors
Zijlstra, Freek J.
Heijmans-Antonissen, Claudia
Huygen, Frank J. P. M.
Niehof, Sjoerd P.
Wesseldijk, Feikje
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-05-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In an earlier study, levels of the proinflammatory cytokines TNF-α and IL-6 are higher in blisters fluid from the complex regional pain syndrome type 1 (CRPS1) side obtained at 6 and 30 months (median) after the initial event.
The aim of this follow-up study is to determine the involvement of these cytokines in long lasting CRPS1.
Twelve CRPS1 patients, with median disease duration of 72 months, participated.
The levels of TNF-α and IL-6 were measured in blister fluid; disease activity was reevaluated by measuring pain and differences in temperature, volume, and mobility between both extremities.
Differences in levels of IL-6 and TNF-α and mobility between both sides were significantly decreased.
Pain and differences in temperature and volume were not significantly altered.
No correlation was found between the cytokines and the disease characteristics.
These results indicate that IL-6 and TNF-α are only partially responsible for the signs and symptoms of CRPS1.
American Psychological Association (APA)
Wesseldijk, Feikje& Huygen, Frank J. P. M.& Heijmans-Antonissen, Claudia& Niehof, Sjoerd P.& Zijlstra, Freek J.. 2008. Six Years Follow-up of the Levels of TNF-α and IL-6 in Patients with Complex Regional Pain Syndrome Type 1. Mediators of Inflammation،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-988147
Modern Language Association (MLA)
Wesseldijk, Feikje…[et al.]. Six Years Follow-up of the Levels of TNF-α and IL-6 in Patients with Complex Regional Pain Syndrome Type 1. Mediators of Inflammation No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-988147
American Medical Association (AMA)
Wesseldijk, Feikje& Huygen, Frank J. P. M.& Heijmans-Antonissen, Claudia& Niehof, Sjoerd P.& Zijlstra, Freek J.. Six Years Follow-up of the Levels of TNF-α and IL-6 in Patients with Complex Regional Pain Syndrome Type 1. Mediators of Inflammation. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-988147
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988147