The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-06-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
In recent years, the study of the peroxisome proliferators activated receptor gamma (PPAR-γ) as a potential target for cancer prevention and therapy has gained a strong interest.
However, the overall biological significance of PPAR-γ in cancer development and progression is still controversial.
While many reports documented antiproliferative effects in human cancer cell and animal models, several studies demonstrating potential tumor promoting actions of PPAR-γ ligands raised considerable concerns about the role of PPAR-γ in human cancers.
Controversy also exists about the role of PPAR-γ in human pancreatic cancers.
The current review summarizes the data about PPAR-γ in pancreatic cancer and highlights the biologically relevant interactions between the cyclooxygenase and PPAR system.
American Psychological Association (APA)
Eibl, Guido. 2008. The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer. PPAR Research،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988195
Modern Language Association (MLA)
Eibl, Guido. The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer. PPAR Research No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-988195
American Medical Association (AMA)
Eibl, Guido. The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988195
