A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer

Joint Authors

Wang, Li Hua
Farrar, William L.
Yang, Xiao Yi

Source

PPAR Research

Issue

Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-12, 12 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2008-05-29

Country of Publication

Egypt

No. of Pages

12

Main Subjects

Biology

Abstract EN

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor and a member of the nuclear receptor superfamily.

PPARγ and its ligands appear to serve diverse biological functions.

In addition to the well-studied effects of PPARγ on metabolism and cellular differentiation, abundant evidence suggests that PPARγ is an important regulator of the immune system and cancers.

Since cytokines are not only key modulators of inflammation with pro- and anti-inflammatory functions but they also can either stimulate or inhibit tumor growth and progression, this review summarizes the role for PPARγ in the regulation of cytokine production and cytokine-mediated signal transduction pathways in immune cells and cancer.

American Psychological Association (APA)

Yang, Xiao Yi& Wang, Li Hua& Farrar, William L.. 2008. A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer. PPAR Research،Vol. 2008, no. 2008, pp.1-12.
https://search.emarefa.net/detail/BIM-988251

Modern Language Association (MLA)

Yang, Xiao Yi…[et al.]. A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer. PPAR Research No. 2008 (2008), pp.1-12.
https://search.emarefa.net/detail/BIM-988251

American Medical Association (AMA)

Yang, Xiao Yi& Wang, Li Hua& Farrar, William L.. A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-12.
https://search.emarefa.net/detail/BIM-988251

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-988251