Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NCNga Mice
Joint Authors
Choi, Sun Eun
Joo, Seong Soo
Bang, Hyoweon
Kim, Ji Young
Park, Kwan Hee
Kim, Jung Shim
Lee, Mi-Kyung
Kim, Eun Joo
Li, Kap-sok
Choi, Young Wook
Lee, Do Ik
Jeong, Mi Sook
Moon, Nam Ju
Seo, Seong Jun
Lee, Min Won
Lee, Chung Soo
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Atopic dermatitis (AD) is a common inflammatory skin disease.
The increasing prevalence and severity of AD have prompted the developments of safer, more effective drugs.
Although topical corticosteroids have been used as first line therapy for AD, their potential side effects limit their clinical applications.
To investigate the effect of hirsutenone (HIR), a diarylheptanoid compound, on AD-like skin lesions and other factors related to immune response is the aim of this paper Th2-related cytokines (IL-4, IL-5, IL-13), eosinophil, IgE inflammatory factors (COX-2, iNOS) levels were reduced in blood, lymphocytes, and tissue after HIR treatment.
These results suggest that HIR might be an effective treatment for AD.
American Psychological Association (APA)
Jeong, Mi Sook& Choi, Sun Eun& Kim, Ji Young& Kim, Jung Shim& Kim, Eun Joo& Park, Kwan Hee…[et al.]. 2010. Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NCNga Mice. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-989327
Modern Language Association (MLA)
Jeong, Mi Sook…[et al.]. Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NCNga Mice. Journal of Immunology Research No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-989327
American Medical Association (AMA)
Jeong, Mi Sook& Choi, Sun Eun& Kim, Ji Young& Kim, Jung Shim& Kim, Eun Joo& Park, Kwan Hee…[et al.]. Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NCNga Mice. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-989327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989327