IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection
Joint Authors
Ashman, Robert B.
Wells, Christine A.
Vijayan, Dipti
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
IL-12 is a cytokine with links to both innate and adaptive immunity systems.
In mice, its deletion leads to acute susceptibility to oral infection with the yeast Candida albicans, whereas such mice are resistant to systemic disease.
However, it is an essential component of the adaptive response that leads to the generation of Th1-type cytokine responses and protection against disseminated disease.
This paper presents an overview of the role of IL-12 in models of systemic and mucosal infection and the possible relationships between them.
American Psychological Association (APA)
Ashman, Robert B.& Vijayan, Dipti& Wells, Christine A.. 2010. IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-990845
Modern Language Association (MLA)
Ashman, Robert B.…[et al.]. IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-990845
American Medical Association (AMA)
Ashman, Robert B.& Vijayan, Dipti& Wells, Christine A.. IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection. Journal of Immunology Research. 2010. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-990845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990845