Natural Immunity to HIV: A Delicate Balance between Strength and Control
Joint Authors
Thibodeau, Valérie
Poudrier, Johanne
Roger, Michel
Source
Journal of Immunology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-11
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Understanding how the mucosal immune system in the human female reproductive tract might prevent or facilitate HIV infection has important implications for the design of effective interventions.
We and others have established cohorts of highly-exposed, HIV-seronegative individuals, such as HIV-uninfected commercial sex workers, who have remained HIV-negative after more than 5 years of active prostitution.
Observations obtained in studies of such individuals, who represent a model of natural immunity to HIV, indicate that HIV resistance may be associated with the host’s capacity to preserve systemic integrity by constraining immune activity and controlling inflammatory conditions at the mucosal point of entry.
This likely necessitates the orchestration of balanced, first-line and adaptive immune responses.
American Psychological Association (APA)
Poudrier, Johanne& Thibodeau, Valérie& Roger, Michel. 2012. Natural Immunity to HIV: A Delicate Balance between Strength and Control. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-996903
Modern Language Association (MLA)
Poudrier, Johanne…[et al.]. Natural Immunity to HIV: A Delicate Balance between Strength and Control. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-996903
American Medical Association (AMA)
Poudrier, Johanne& Thibodeau, Valérie& Roger, Michel. Natural Immunity to HIV: A Delicate Balance between Strength and Control. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-996903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-996903