Early Hearing-Impairment Results in Crossmodal Reorganization of Ferret Core Auditory Cortex
المؤلفون المشاركون
Meredith, M. Alex
Allman, Brian L.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-19
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Numerous investigations of cortical crossmodal plasticity, most often in congenital or early-deaf subjects, have indicated that secondary auditory cortical areas reorganize to exhibit visual responsiveness while the core auditory regions are largely spared.
However, a recent study of adult-deafened ferrets demonstrated that core auditory cortex was reorganized by the somatosensory modality.
Because adult animals have matured beyond their critical period of sensory development and plasticity, it was not known if adult-deafening and early-deafening would generate the same crossmodal results.
The present study used young, ototoxically-lesioned ferrets (n=3) that, after maturation (avg.
= 173 days old), showed significant hearing deficits (avg.
threshold = 72 dB SPL).
Recordings from single-units (n=132) in core auditory cortex showed that 72% were activated by somatosensory stimulation (compared to 1% in hearing controls).
In addition, tracer injection into early hearing-impaired core auditory cortex labeled essentially the same auditory cortical and thalamic projection sources as seen for injections in the hearing controls, indicating that the functional reorganization was not the result of new or latent projections to the cortex.
These data, along with similar observations from adult-deafened and adult hearing-impaired animals, support the recently proposed brainstem theory for crossmodal plasticity induced by hearing loss.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meredith, M. Alex& Allman, Brian L.. 2012. Early Hearing-Impairment Results in Crossmodal Reorganization of Ferret Core Auditory Cortex. Neural Plasticity،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1002439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meredith, M. Alex& Allman, Brian L.. Early Hearing-Impairment Results in Crossmodal Reorganization of Ferret Core Auditory Cortex. Neural Plasticity No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-1002439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meredith, M. Alex& Allman, Brian L.. Early Hearing-Impairment Results in Crossmodal Reorganization of Ferret Core Auditory Cortex. Neural Plasticity. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-1002439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1002439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر