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Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia
المؤلفون المشاركون
Pantula, Hiranmayi
McDonald, Kathryn
Leroi, Iracema
Harbishettar, Vijay
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Neuropsychiatric symptoms commonly complicate Parkinson’s disease (PD), however the presence of such symptoms in mild cognitive impairment (PD-MCI) specifically has not yet been well described.
The objective of this study was to examine and compare the prevalence and profile of neuropsychiatric symptoms in patients with PD-MCI (n = 48) to those with PD and no cognitive impairment (PD-NC, n = 54) and to those with dementia in PD (PDD, n = 25).
PD-MCI and PDD were defined using specific consensus criteria, and neuropsychiatric symptoms were assessed with the 12-item Neuropsychiatric Inventory (NPI).
Self-rated apathy, depression, and anxiety rating scales were also administered.
Over 79% of all participants reported at least one neuropsychiatric symptom in the past month.
The proportion in each group who had total NPI scores of ≥4 (“clinically significant”) was as follows: PD-NC, 64.8%; PD-MCI, 62%; PDD 76%.
Apathy was reported in almost 50% of those with PD-MCI and PDD, and it was an important neuropsychiatric symptom differentiating PD-MCI from PD-NC.
Psychosis (hallucinations and delusions) increased from 12.9% in PD-NC group; 16.7% in PD-MCI group; and 48% in PDD group.
Identifying neuropsychiatric symptoms in PD-MCI may have implications for ascertaining conversion to dementia in PD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Leroi, Iracema& Pantula, Hiranmayi& McDonald, Kathryn& Harbishettar, Vijay. 2012. Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia. Parkinson’s Disease،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1002767
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Leroi, Iracema…[et al.]. Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia. Parkinson’s Disease No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-1002767
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Leroi, Iracema& Pantula, Hiranmayi& McDonald, Kathryn& Harbishettar, Vijay. Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia. Parkinson’s Disease. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1002767
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1002767
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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