Adipose-Derived Mesenchymal StromalStem Cells: Tissue Localization, Characterization, and Heterogeneity
المؤلفون المشاركون
Baer, Patrick C.
Geiger, Helmut
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-12
دولة النشر
مصر
عدد الصفحات
11
الملخص EN
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources.
It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal stromal/stem cells (ASCs) yields a high amount of stem cells, which is essential for stem-cell-based therapies and tissue engineering.
Several studies have provided evidence that ASCs in situ reside in a perivascular niche, whereas the exact localization of ASCs in native adipose tissue is still under debate.
ASCs are isolated by their capacity to adhere to plastic.
Nevertheless, recent isolation and culture techniques lack standardization.
Cultured cells are characterized by their expression of characteristic markers and their capacity to differentiate into cells from meso-, ecto-, and entodermal lineages.
ASCs possess a high plasticity and differentiate into various cell types, including adipocytes, osteoblasts, chondrocytes, myocytes, hepatocytes, neural cells, and endothelial and epithelial cells.
Nevertheless, recent studies suggest that ASCs are a heterogeneous mixture of cells containing subpopulations of stem and more committed progenitor cells.
This paper summarizes and discusses the current knowledge of the tissue localization of ASCs in situ, their characterization and heterogeneity in vitro, and the lack of standardization in isolation and culture methods.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baer, Patrick C.& Geiger, Helmut. 2012. Adipose-Derived Mesenchymal StromalStem Cells: Tissue Localization, Characterization, and Heterogeneity. Stem Cells International،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1003104
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baer, Patrick C.& Geiger, Helmut. Adipose-Derived Mesenchymal StromalStem Cells: Tissue Localization, Characterization, and Heterogeneity. Stem Cells International No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-1003104
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baer, Patrick C.& Geiger, Helmut. Adipose-Derived Mesenchymal StromalStem Cells: Tissue Localization, Characterization, and Heterogeneity. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1003104
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1003104
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر