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Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study
المؤلفون المشاركون
Forni Ogna, Valentina
Pruijm, Menno
Zweiacker, Carole
Wuerzner, Grégoire
Tousset, Eric
Burnier, Michel
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background/Aims.
One of the causes of uncontrolled secondary hyperparathyroidism (sHPT) is patient’s poor drug adherence.
We evaluated the clinical benefits of an integrated care approach on the control of sHPT by cinacalcet.
Methods.
Prospective, randomized, controlled, multicenter, open-label study.
Fifty hemodialysis patients on a stable dose of cinacalcet were randomized to an integrated care approach (IC) or usual care approach (UC).
In the IC group, cinacalcet adherence was monitored using an electronic system.
Results were discussed with the patients in motivational interviews, and drug prescription adapted accordingly.
In the UC group, drug adherence was monitored, but results were not available.
Results.
At six months, 84% of patients in the IC group achieved recommended iPTH targets versus 55% in the UC group (P=0.04).
The mean cinacalcet taking adherence improved by 10.8% in the IC group and declined by 5.3% in the UC group (P=0.02).
Concomitantly, the mean dose of cinacalcet was reduced by 7.2 mg/day in the IC group and increased by 6.4 mg/day in the UC group (P=0.03).
Conclusions.
The use of a drug adherence monitoring program in the management of sHPT in hemodialysis patients receiving cinacalcet improves drug adherence and iPTH control and allows a reduction in the dose of cinacalcet.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Forni Ogna, Valentina& Pruijm, Menno& Zweiacker, Carole& Wuerzner, Grégoire& Tousset, Eric& Burnier, Michel. 2013. Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1003256
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Forni Ogna, Valentina…[et al.]. Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1003256
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Forni Ogna, Valentina& Pruijm, Menno& Zweiacker, Carole& Wuerzner, Grégoire& Tousset, Eric& Burnier, Michel. Clinical Benefits of an Adherence Monitoring Program in the Management of Secondary Hyperparathyroidism with Cinacalcet: Results of a Prospective Randomized Controlled Study. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1003256
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1003256
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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