Content of Trans Fatty Acids in Human Cheek Epithelium: Comparison with Serum and Adipose Tissue

الملخص EN

Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices.

Measuring TFA is an arduous task because of the need for fat biopsies.

This study identifies a tissue, which can be easily accessed for analytical measurement of trans fatty acid.

In this cross-sectional study, fatty acid in adipose tissue, cheek epithelium, and blood samples were assessed by gas chromatography.

Spearman correlation coefficient was computed to study the correlation of fatty acid distribution among the three tissues.

The correlation coefficient of total trans fatty acid between cheek epithelium and serum was 0.30 (P<0.02) and between cheek epithelium and adipose tissue was 0.33 (P<0.019).

This study is the first to report trans fatty acid profile in cheek epithelium giving scope for utilizing the cheek epithelium as a tissue for objective assessment of trans fatty acid intake.