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Development of Composite Scaffolds for Load-Bearing Segmental Bone Defects
المؤلفون المشاركون
Pilia, Marcello
Guda, Teja
Appleford, Mark
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-29
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
The need for a suitable tissue-engineered scaffold that can be used to heal load-bearing segmental bone defects (SBDs) is both immediate and increasing.
During the past 30 years, various ceramic and polymer scaffolds have been investigated for this application.
More recently, while composite scaffolds built using a combination of ceramics and polymeric materials are being investigated in a greater number, very few products have progressed from laboratory benchtop studies to preclinical testing in animals.
This review is based on an exhaustive literature search of various composite scaffolds designed to serve as bone regenerative therapies.
We analyzed the benefits and drawbacks of different composite scaffold manufacturing techniques, the properties of commonly used ceramics and polymers, and the properties of currently investigated synthetic composite grafts.
To follow, a comprehensive review of in vivo models used to test composite scaffolds in SBDs is detailed to serve as a guide to design appropriate translational studies and to identify the challenges that need to be overcome in scaffold design for successful translation.
This includes selecting the animal type, determining the anatomical location within the animals, choosing the correct study duration, and finally, an overview of scaffold performance assessment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pilia, Marcello& Guda, Teja& Appleford, Mark. 2013. Development of Composite Scaffolds for Load-Bearing Segmental Bone Defects. BioMed Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004325
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pilia, Marcello…[et al.]. Development of Composite Scaffolds for Load-Bearing Segmental Bone Defects. BioMed Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1004325
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pilia, Marcello& Guda, Teja& Appleford, Mark. Development of Composite Scaffolds for Load-Bearing Segmental Bone Defects. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004325
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004325
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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