![](/images/graphics-bg.png)
Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells
المؤلفون المشاركون
Richard, Vinitha
Nair, Madhumathy G.
Santhosh Kumar, T. R.
Pillai, M. Radhakrishna
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Classically, isolation of CSCs from tumors exploits the detection of cell surface markers associated with normal stem cells.
Invariable expression of these cell surface markers in almost all proliferating tumor cells that albeit impart specific functionality, the universality, and clinical credibility of CSC phenotype based on markers is still dubious.
Side Population (SP) cells, as defined by Hoechst dye exclusion in flow cytometry, have been identified in many solid tumors and cell lines and the SP phenotype can be considered as an enriched source of stem cells as well as an alternative source for the isolation of cancer stem cells especially when molecular markers for stem cells are unknown.
SP cells may be responsible for the maintenance and propagation of tumors and the proportion of SP cells may be a predictor of patient outcome.
Several of these markers used in cell sorting have emerged as prognostic markers of disease progression though it is seen that the development of new CSC-targeted strategies is often hindered by poor understanding of their regulatory networks and functions.
This review intends to appraise the experimental progress towards enhanced isolation and drug screening based on property of acquired chemoresistance of cancer stem cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Richard, Vinitha& Nair, Madhumathy G.& Santhosh Kumar, T. R.& Pillai, M. Radhakrishna. 2013. Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004497
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Richard, Vinitha…[et al.]. Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004497
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Richard, Vinitha& Nair, Madhumathy G.& Santhosh Kumar, T. R.& Pillai, M. Radhakrishna. Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004497
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004497
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)