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Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions
المؤلفون المشاركون
Nieguitsila, Adélaïde
Frutos, Roger
Moulia, Catherine
Lhermitte-Vallarino, Nathaly
Bain, Odile
Gavotte, Laurent
Martin, Coralie
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-09
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Filariae are a leading cause of infections which are responsible for serious dermatological, ocular, and vascular lesions.
Infective third stage larvae (L3) are transmitted through the bite of a haematophagous vector.
Litomosoides sigmodontis is a well-established model of filariasis in the mouse, with the vector being the mite Ornithonyssus bacoti.
The aim of the study was to analyse the filarial infection in mites to determine the consequences of filarial infection in the blood-feeding and the reproduction of mites as well as in the regulation of vector-induced inflammation in the mouse skin.
Firstly, L3 are unevenly distributed throughout the host population and the majority of the population harbours a moderate infection (1 to 6 L3).
Filarial infection does not significantly affect the probing delay for blood feeding.
The number of released protonymphs is lower in infected mites but is not correlated with the L3 burden.
Finally, induced excreted proteins from infected mites but not from uninfected mites stimulate TNF-α and the neutrophil-chemoattractant KC production by antigen-presenting cells (APCs).
Altogether, these results describe the modification of the mite behavior under filarial infection and suggest that the immunomodulatory capacity of the mite may be modified by the presence of the parasite, hindering its defensive ability towards the vertebrate host.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nieguitsila, Adélaïde& Frutos, Roger& Moulia, Catherine& Lhermitte-Vallarino, Nathaly& Bain, Odile& Gavotte, Laurent…[et al.]. 2013. Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004653
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nieguitsila, Adélaïde…[et al.]. Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004653
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nieguitsila, Adélaïde& Frutos, Roger& Moulia, Catherine& Lhermitte-Vallarino, Nathaly& Bain, Odile& Gavotte, Laurent…[et al.]. Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004653
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004653
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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