Assessing Competence of Broccoli Consumption on Inflammatory and Antioxidant Pathways in Restraint-Induced Models: Estimation in Rat Hippocampus and Prefrontal Cortex
المؤلفون المشاركون
Khalaj, Leila
Chavoshi Nejad, Sara
Mohammadi, Marzieh
Sarraf Zadeh, Sadaf
Hossein Pour, Marieh
Ashabi, Ghorbangol
Khodagholi, Fariba
Ahmadiani, Abolhassan
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-11
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
A growing body of evidence advocated the protective and therapeutic potential of natural compounds and phytochemicals used in diets against pathological conditions.
Herein, the outcome of dietary whole broccoli consumption prior to restraint stress has been investigated in the hippocampus and prefrontal cortex of male rats, two important regions involved in the processing of responses to stressful events.
Interestingly, a region-specific effect was detected regarding some of antioxidant defense system factors: nuclear factor erythroid-derived 2-related factor 2 (Nrf-2) antioxidant pathway, mitochondrial prosurvival proteins involved in mitochondrial biogenesis, and apoptotic cell death proteins.
Dietary broccoli supplementation modulated the restraint-induced changes towards a consistent overall protection in the hippocampus.
In the prefrontal cortex, however, despite activation of most of the protective factors, presumably as an attempt to save the system against the stress insult, some detrimental outcomes such as induced malate dehydrogenase (MDA) level and cleaved form of caspase-3 were detectable.
Such diversity may be attributed in one hand to the different basic levels and/or availability of defensive mechanisms within the two studied cerebral regions, and on the other hand to the probable dose-dependent and hormetic effects of whole broccoli.
More experiments are essential to demonstrate these assumptions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khalaj, Leila& Chavoshi Nejad, Sara& Mohammadi, Marzieh& Sarraf Zadeh, Sadaf& Hossein Pour, Marieh& Ashabi, Ghorbangol…[et al.]. 2013. Assessing Competence of Broccoli Consumption on Inflammatory and Antioxidant Pathways in Restraint-Induced Models: Estimation in Rat Hippocampus and Prefrontal Cortex. BioMed Research International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1004671
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khalaj, Leila…[et al.]. Assessing Competence of Broccoli Consumption on Inflammatory and Antioxidant Pathways in Restraint-Induced Models: Estimation in Rat Hippocampus and Prefrontal Cortex. BioMed Research International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-1004671
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khalaj, Leila& Chavoshi Nejad, Sara& Mohammadi, Marzieh& Sarraf Zadeh, Sadaf& Hossein Pour, Marieh& Ashabi, Ghorbangol…[et al.]. Assessing Competence of Broccoli Consumption on Inflammatory and Antioxidant Pathways in Restraint-Induced Models: Estimation in Rat Hippocampus and Prefrontal Cortex. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1004671
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004671
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر