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Triterpenes and the Antimycobacterial Activity of Duroia macrophylla Huber (Rubiaceae)
المؤلفون المشاركون
Martins, Daiane
Carrion, Lillian Lucas
Ramos, Daniela Fernandes
Salomé, Kahlil Schwanka
da Silva, Pedro Eduardo Almeida
Barison, Andersson
Nunez, Cecilia Veronica
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Duroia macrophylla popularly known as “cabeça-de-urubú,” “apuruí,” or “puruí-grande-da-mata” occurs in the Amazon Forest.
Its leaves and branches were collected twice and extracted with dichloromethane and methanol.
All extracts were subjected to phytochemical investigation and terpenes and flavonoids were found in all dichloromethane and methanol extracts, respectively.
Methanol extracts from both branches (1st collection) and leaves (2nd collection) presented hydrolyzed tannins, yet alkaloids were only detected in the dichloromethane and methanol extracts from branches at the 2nd collection.
Phenol compounds were found in both dichloromethane extracts’ collections.
The action of every extract was assayed against Mycobacterium tuberculosis (RMPr, H37Rv, and INHr strains), showing that the dichloromethane extract from leaves (1st collection) has the major biological activity, with a MIC of 6.25 μg/mL for the INHr strain, 25.0 μg/mL for the RMPr strain, and ≤6.25 μg/mL for the H37Rv strain.
The chromatographic fractioning of the dichloromethane extract from leaves (1st collection) yielded the isolation of two triterpenes: oleanolic and ursolic acids, which were identified by NMR analysis and reported for the first time in the Duroia genus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Martins, Daiane& Carrion, Lillian Lucas& Ramos, Daniela Fernandes& Salomé, Kahlil Schwanka& da Silva, Pedro Eduardo Almeida& Barison, Andersson…[et al.]. 2013. Triterpenes and the Antimycobacterial Activity of Duroia macrophylla Huber (Rubiaceae). BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1004712
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Martins, Daiane…[et al.]. Triterpenes and the Antimycobacterial Activity of Duroia macrophylla Huber (Rubiaceae). BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1004712
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Martins, Daiane& Carrion, Lillian Lucas& Ramos, Daniela Fernandes& Salomé, Kahlil Schwanka& da Silva, Pedro Eduardo Almeida& Barison, Andersson…[et al.]. Triterpenes and the Antimycobacterial Activity of Duroia macrophylla Huber (Rubiaceae). BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1004712
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004712
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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