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Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study
المؤلفون المشاركون
Xu, Cui-Ping
Zhang, Shou-Wen
Fang, Tie
Manxiu, Ma
Chencan, Qian
Huafu, Chen
Zhu, Hong-Wei
Li, Yong-Jie
Zuxiang, Liu
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-26
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Functional connectivity has been correlated with a patient’s level of consciousness and has been found to be altered in several neuropsychiatric disorders.
Absence epilepsy patients, who experience a loss of consciousness, are assumed to suffer from alterations in thalamocortical networks; however, previous studies have not explored the changes at a functional module level.
We used resting-state functional magnetic resonance imaging to examine the alteration in functional connectivity that occurs in absence epilepsy patients.
By parcellating the brain into 90 brain regions/nodes, we uncovered an altered functional connectivity within and between functional modules.
Some brain regions had a greater number of altered connections and therefore behaved as key nodes in the changed network pattern; these regions included the superior frontal gyrus, the amygdala, and the putamen.
In particular, the superior frontal gyrus demonstrated both an increased value of connections with other nodes of the frontal default mode network and a decreased value of connections with the limbic system.
This divergence is positively correlated with epilepsy duration.
These findings provide a new perspective and shed light on how functional connectivity and the balance of within/between module connections may contribute to both the state of consciousness and the development of absence epilepsy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Cui-Ping& Zhang, Shou-Wen& Fang, Tie& Manxiu, Ma& Chencan, Qian& Huafu, Chen…[et al.]. 2013. Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study. BioMed Research International،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1004992
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Cui-Ping…[et al.]. Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study. BioMed Research International No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-1004992
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Cui-Ping& Zhang, Shou-Wen& Fang, Tie& Manxiu, Ma& Chencan, Qian& Huafu, Chen…[et al.]. Altered Functional Connectivity within and between Brain Modules in Absence Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1004992
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004992
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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