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Preliminary Characterization of Genipin-Cross-Linked Silk SericinPoly(vinyl alcohol) Films as Two-Dimensional Wound Dressings for the Healing of Superficial Wounds
المؤلفون المشاركون
Aramwit, Pornanong
Siritientong, Tippawan
Ratanavaraporn, Juthamas
Srichana, Teerapol
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-10
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The genipin-cross-linked silk sericin/poly(vinyl alcohol) (PVA) films were developed aiming to be applied as two-dimensional wound dressings for the treatment of superficial wounds.
The effects of genipin cross-linking concentration on the physical and biological properties of the films were investigated.
The genipin-cross-linked silk sericin/PVA films showed the increased surface density, tensile strength, and percentage of elongation, but decreased percentage of light transmission, water vapor transmission rate, and water swelling, compared to the non-cross-linked films.
This explained that the cross-linking bonds between genipin and silk sericin would reduce the mobility of molecular chains within the films, resulting in the more rigid molecular structure.
Silk sericin was released from the genipin-cross-linked films in a sustained manner.
In addition, either L929 mouse fibroblast or HaCat keratinocyte cells showed high percentage of viability when cultured on the silk sericin/PVA films cross-linked with 0.075 and 0.1% w/v genipin.
The in vivo safety test performed according to ISO 10993-6 confirmed that the genipin-cross-linked silk sericin/PVA films were safe for the medical usages.
The efficacy of the films for the treatment of superficial skin wounds will be further investigated in vivo and clinically.
The genipin-cross-linked silk sericin/PVA films would be promising choices of two-dimensional wound dressings for the treatment of superficial wounds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Siritientong, Tippawan& Ratanavaraporn, Juthamas& Srichana, Teerapol& Aramwit, Pornanong. 2013. Preliminary Characterization of Genipin-Cross-Linked Silk SericinPoly(vinyl alcohol) Films as Two-Dimensional Wound Dressings for the Healing of Superficial Wounds. BioMed Research International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1005370
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Siritientong, Tippawan…[et al.]. Preliminary Characterization of Genipin-Cross-Linked Silk SericinPoly(vinyl alcohol) Films as Two-Dimensional Wound Dressings for the Healing of Superficial Wounds. BioMed Research International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-1005370
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Siritientong, Tippawan& Ratanavaraporn, Juthamas& Srichana, Teerapol& Aramwit, Pornanong. Preliminary Characterization of Genipin-Cross-Linked Silk SericinPoly(vinyl alcohol) Films as Two-Dimensional Wound Dressings for the Healing of Superficial Wounds. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1005370
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1005370
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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