The Immune Factors Involved in the Pathogenesis, Diagnosis, and Treatment of Sjogren's Syndrome
المؤلفون المشاركون
Xiao, Lan
Cheng, Qian
Chen, Qian-ming
An, Shu
Wang, Yating
Lei, Lei
Jiang, Chun-miao
Wang, Jun
Huang, Yi-fan
Yu, Wen-jing
Gou, Yong-chao
المصدر
Journal of Immunology Research
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Sjogren's syndrome (SS) is a systemic, autoimmune disorder characterized by salivary insufficiency and lymphocytic infiltration of the exocrine glands.
Even though the mechanism of its pathology and progression has been researched ever since its discovery, the roles of different parts of immune system remain inconclusive.
There is no straightforward and simple theory for the pathogenesis and diagnosis of Sjogren’s syndrome because of the multiple kinds and functions of autoantibodies, changing proportion of different T-lymphocyte subsets with the progression of disease, unsuspected abilities of B lymphocytes discovered recently, crosstalk between cytokines connecting the factors mentioned previously, and genetic predisposition that contributes to the initiation of this disease.
On the other hand, the number of significant reports and open-label studies of B-cell depletion therapy showing clinical efficacy in sjogren’s syndrome has continued to accumulate, which provides a promising future for the patients.
In a word, further elucidation of the role of different components of the immune system will open avenues for better diagnosis and treatment of SS, whose current management is still mainly supportive.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Yi-fan& Cheng, Qian& Jiang, Chun-miao& An, Shu& Xiao, Lan& Gou, Yong-chao…[et al.]. 2013. The Immune Factors Involved in the Pathogenesis, Diagnosis, and Treatment of Sjogren's Syndrome. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1006479
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Yi-fan…[et al.]. The Immune Factors Involved in the Pathogenesis, Diagnosis, and Treatment of Sjogren's Syndrome. Journal of Immunology Research No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1006479
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Yi-fan& Cheng, Qian& Jiang, Chun-miao& An, Shu& Xiao, Lan& Gou, Yong-chao…[et al.]. The Immune Factors Involved in the Pathogenesis, Diagnosis, and Treatment of Sjogren's Syndrome. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1006479
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1006479
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر