Regulation of Recombination between gtfBgtfC Genes in Streptococcus mutans by Recombinase A
المؤلفون المشاركون
Inagaki, Satoko
Fujita, Kazuyo
Takashima, Yukiko
Nagayama, Kayoko
Ardin, Arifah C.
Matsumi, Yuki
Matsumoto-Nakano, Michiyo
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-17
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Streptococcus mutans produces 3 types of glucosyltransferases (GTFs), whose cooperative action is essential for cellular adhesion.
The recombinase A (RecA) protein is required for homologous recombination.
In our previous study, we isolated several strains with a smooth colony morphology and low GTF activity, characteristics speculated to be derived from the GTF fusions.
The purpose of the present study was to investigate the mechanism of those fusions.
S.
mutans strain MT8148 was grown in the presence of recombinant RecA (rRecA) protein, after which smooth colonies were isolated.
The biological functions and sequences of the gtfB and gtfC genes of this as well as other clinical strains were determined.
The sucrose-dependent adherence rates of those strains were reduced as compared to that of MT8148.
Determination of the sequences of the gtfB and gtfC genes showed that an approximately 3500 bp region was deleted from the area between them.
Furthermore, expression of the recA gene was elevated in those strains as compared to MT8148.
These results suggest that RecA has an important role in fusions of gtfB and gtfC genes, leading to alteration of colony morphology and reduction in sucrose-dependent adhesion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Inagaki, Satoko& Fujita, Kazuyo& Takashima, Yukiko& Nagayama, Kayoko& Ardin, Arifah C.& Matsumi, Yuki…[et al.]. 2013. Regulation of Recombination between gtfBgtfC Genes in Streptococcus mutans by Recombinase A. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1012195
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Inagaki, Satoko…[et al.]. Regulation of Recombination between gtfBgtfC Genes in Streptococcus mutans by Recombinase A. The Scientific World Journal No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1012195
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Inagaki, Satoko& Fujita, Kazuyo& Takashima, Yukiko& Nagayama, Kayoko& Ardin, Arifah C.& Matsumi, Yuki…[et al.]. Regulation of Recombination between gtfBgtfC Genes in Streptococcus mutans by Recombinase A. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1012195
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1012195
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر