A Real-World, Multicenter Assessment of Drugs Requiring Weight-Based Calculations in Overweight, Adult Critically Ill Patients
المؤلفون المشاركون
Kane-Gill, Sandra L.
Wytiaz, Nicholas P.
Thompson, Lisa M.
Muzykovsky, Karina
Buckley, Mitchell S.
Cohen, Henry
Seybert, Amy L.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Prescribing appropriate doses of drugs requiring weight-based dosing is challenging in overweight patients due to a lack of data.
With 68% of the US population considered overweight and these patients being at an increased risk for hospitalization, clinicians need guidance on dosing weight-based drugs.
The purpose of this study was to identify “real-world” dose ranges of high-risk medications administered via continuous infusion requiring weight-based dosing and determine the reasons for dosing changes (ineffectiveness or adverse drug reactions).
A prospective, multicenter, observational study was conducted in four intensive care units at three institutions.
A total of 857 medication orders representing 11 different high-risk medications in 173 patients were reviewed.
It was noted that dosing did not increase in proportion to weight classification.
Overall, 14 adverse drug reactions occurred in nine patients with more in overweight patients (9 of 14).
A total of 75% of orders were discontinued due to ineffectiveness in groups with higher body mass indexes.
Ineffectiveness leads to dosing adjustments resulting in the opportunity for medication errors.
Also, the frequent dosing changes further demonstrate our lack of knowledge of appropriate dosing for this population.
Given the medications’ increased propensity to cause harm, institutions should aggressively monitor these medications in overweight patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kane-Gill, Sandra L.& Wytiaz, Nicholas P.& Thompson, Lisa M.& Muzykovsky, Karina& Buckley, Mitchell S.& Cohen, Henry…[et al.]. 2013. A Real-World, Multicenter Assessment of Drugs Requiring Weight-Based Calculations in Overweight, Adult Critically Ill Patients. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1013114
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kane-Gill, Sandra L.…[et al.]. A Real-World, Multicenter Assessment of Drugs Requiring Weight-Based Calculations in Overweight, Adult Critically Ill Patients. The Scientific World Journal No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1013114
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kane-Gill, Sandra L.& Wytiaz, Nicholas P.& Thompson, Lisa M.& Muzykovsky, Karina& Buckley, Mitchell S.& Cohen, Henry…[et al.]. A Real-World, Multicenter Assessment of Drugs Requiring Weight-Based Calculations in Overweight, Adult Critically Ill Patients. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1013114
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1013114
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر