Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses
المؤلفون المشاركون
Alanazi, Humidah
Semlali, Abdelhabib
Perraud, Laura
Chmielewski, Witold
Zakrzewski, Andrew
Rouabhia, Mahmoud
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-11
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
The predisposition of cigarette smokers for development of respiratory and oral bacterial infections is well documented.
Cigarette smoke can also contribute to yeast infection.
The aim of this study was to investigate the effect of cigarette smoke condensate (CSC) on C.
albicans transition, chitin content, and response to environmental stress and to examine the interaction between CSC-pretreated C.
albicans and normal human gingival fibroblasts.
Following exposure to CSC, C.
albicans transition from blastospore to hyphal form increased.
CSC-pretreated yeast cells became significantly (P<0.01) sensitive to oxidation but significantly (P<0.01) resistant to both osmotic and heat stress.
CSC-pretreated C.
albicans expressed high levels of chitin, with 2- to 8-fold recorded under hyphal conditions.
CSC-pretreated C.
albicans adhered better to the gingival fibroblasts, proliferated almost three times more and adapted into hyphae, while the gingival fibroblasts recorded a significantly (P<0.01) slow growth rate but a significantly higher level of IL-1β when in contact with CSC-pretreated C.
albicans.
CSC was thus able to modulate both C.
albicans transition through the cell wall chitin content and the interaction between C.
albicans and normal human gingival fibroblasts.
These findings may be relevant to fungal infections in the oral cavity in smokers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alanazi, Humidah& Semlali, Abdelhabib& Perraud, Laura& Chmielewski, Witold& Zakrzewski, Andrew& Rouabhia, Mahmoud. 2014. Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1016663
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alanazi, Humidah…[et al.]. Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1016663
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alanazi, Humidah& Semlali, Abdelhabib& Perraud, Laura& Chmielewski, Witold& Zakrzewski, Andrew& Rouabhia, Mahmoud. Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1016663
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1016663
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر