Bilateral Lung Transplantation in a Patient with Humoral Immune Deficiency: A Case Report with Review of the Literature
المؤلفون المشاركون
Farmer, Jocelyn R.
Sokol, Caroline L.
Bonilla, Francisco A.
Murali, Mandakolathur R.
Kradin, Richard L.
Astor, Todd L.
Walter, Jolan E.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Humoral immune deficiencies have been associated with noninfectious disease complications including autoimmune cytopenias and pulmonary disease.
Herein we present a patient who underwent splenectomy for autoimmune cytopenias and subsequently was diagnosed with humoral immune deficiency in the context of recurrent infections.
Immunoglobulin analysis prior to initiation of intravenous immunoglobulin (IVIG) therapy was notable for low age-matched serum levels of IgA (11 mg/dL), IgG2 (14 mg/L), and IgG4 (5 mg/L) with a preserved total level of IgG.
Flow cytometry was remarkable for B cell maturation arrest at the IgM+/IgD+ stage.
Selective screening for known primary immune deficiency-causing genetic defects was negative.
The disease course was uniquely complicated by the development of pulmonary arteriovenous malformations (AVMs), ultimately requiring bilateral lung transplantation in 2012.
This is a patient with humoral immune deficiency that became apparent only after splenectomy, which argues for routine immunologic evaluation prior to vaccination and splenectomy.
Lung transplantation is a rare therapeutic endpoint and to our knowledge has never before been described in a patient with humoral immune deficiency for the indication of pulmonary AVMs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farmer, Jocelyn R.& Sokol, Caroline L.& Bonilla, Francisco A.& Murali, Mandakolathur R.& Kradin, Richard L.& Astor, Todd L.…[et al.]. 2014. Bilateral Lung Transplantation in a Patient with Humoral Immune Deficiency: A Case Report with Review of the Literature. Case Reports in Immunology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1017123
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farmer, Jocelyn R.…[et al.]. Bilateral Lung Transplantation in a Patient with Humoral Immune Deficiency: A Case Report with Review of the Literature. Case Reports in Immunology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1017123
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farmer, Jocelyn R.& Sokol, Caroline L.& Bonilla, Francisco A.& Murali, Mandakolathur R.& Kradin, Richard L.& Astor, Todd L.…[et al.]. Bilateral Lung Transplantation in a Patient with Humoral Immune Deficiency: A Case Report with Review of the Literature. Case Reports in Immunology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1017123
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1017123
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر