Synthesis and study of some fused substituted 1, 3, 4-thiadiazoles and 1, 2, 4-triazoles from 4-chloro- phenoxy acetic acid and 2, 4-dichlorophenoxy acetic acid
العناوين الأخرى
تحضير ودراسة بعض المعوضات الملتحمة ل 4،3،1-ثيادايازول و 4،2،1-ترايازول من 4-كلورو-فينوكسي حامض الأسيتيك و 4،2-ثنائي كلورو فينوكسي حامض الأسيتيك
المؤلف
المصدر
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
العدد
المجلد 29، العدد 3 (30 سبتمبر/أيلول 2020)، ص ص. 218-226، 9ص.
الناشر
جامعة الموصل كلية التربية للعلوم الصرفة
تاريخ النشر
2020-09-30
دولة النشر
العراق
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
In this work the synthesis of some substituted 1, 2, 4-triazoles and five ring system's reported.
2-(4-Chlorophenoxy) acetic acid (S1) was synthesis from corresponding substituted phenol by its reaction with chloroacetic acid in sodium hydroxide solution, the acids (Q1 and S1) esterified with methanol and sulfuric acid to give esters (Q2 and S2) which converted to acid hydrazides (Q3 and S3) by their reaction with hydrazine hydrate in ethanol.
The acid hydrazides (Q3 and S3) were treated with carbon disulfide in potassium hydroxide solution to give potassium salts (Q4 and S4) the formed salts were treated with hydrazine hydrate to give substituted 4-amino-1, 2, 4-triazoles (Q5 and S5).
4-Amino-1, 2, 4-Triazole (Q5 and S5) were converted to (Q6 and S6), (Q9 and S9) and (Q10 and S10) by treating with CS2 in pyridine, urea and chloroacetic acid.
While reaction of 4-amino-1, 2, 4-triazole (Q5 and S5) with phenyl isothiocyanate gave thiosemicarbazide derivatives (Q7 and S7) that converted to N-phenyl substituted 1, 2, 4-triazole (Q8 and S8).
The structures of the synthesized compounds were confirmed by physical and spectral In this work the synthesis of some substituted 1, 2, 4-triazoles and five ring system's reported.
2-(4-Chlorophenoxy) acetic acid (S1) was synthesis from corresponding substituted phenol by its reaction with chloroacetic acid in sodium hydroxide solution, the acids (Q1 and S1) esterified with methanol and sulfuric acid to give esters (Q2 and S2) which converted to acid hydrazides (Q3 and S3) by their reaction with hydrazine hydrate in ethanol.
The acid hydrazides (Q3 and S3) were treated with carbon disulfide in potassium hydroxide solution to give potassium salts (Q4 and S4) the formed salts were treated with hydrazine hydrate to give substituted 4-amino-1, 2, 4-triazoles (Q5 and S5).
4-Amino-1, 2, 4-Triazole (Q5 and S5) were converted to (Q6 and S6), (Q9 and S9) and (Q10 and S10) by treating with CS2 in pyridine, urea and chloroacetic acid.
While reaction of 4-amino-1, 2, 4-triazole (Q5 and S5) with phenyl isothiocyanate gave thiosemicarbazide derivatives (Q7 and S7) that converted to N-phenyl substituted 1, 2, 4-triazole (Q8 and S8).
The structures of the synthesized compounds were confirmed by physical and spectral data.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Uthman, Mudar Akram. 2020. Synthesis and study of some fused substituted 1, 3, 4-thiadiazoles and 1, 2, 4-triazoles from 4-chloro- phenoxy acetic acid and 2, 4-dichlorophenoxy acetic acid. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 29, no. 3, pp.218-226.
https://search.emarefa.net/detail/BIM-1018513
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Uthman, Mudar Akram. Synthesis and study of some fused substituted 1, 3, 4-thiadiazoles and 1, 2, 4-triazoles from 4-chloro- phenoxy acetic acid and 2, 4-dichlorophenoxy acetic acid. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 29, no. 3 (2020), pp.218-226.
https://search.emarefa.net/detail/BIM-1018513
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Uthman, Mudar Akram. Synthesis and study of some fused substituted 1, 3, 4-thiadiazoles and 1, 2, 4-triazoles from 4-chloro- phenoxy acetic acid and 2, 4-dichlorophenoxy acetic acid. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2020. Vol. 29, no. 3, pp.218-226.
https://search.emarefa.net/detail/BIM-1018513
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 225-226
رقم السجل
BIM-1018513
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر