Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study
المؤلفون المشاركون
Phetkate, Pratya
U-pratya, Yaowalak
Kietinun, Somboon
Kummalue, Tanawan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Searching for drugs or herbal formulations to improve the immunity of HIV/AIDS positive people is an important issue for researchers in this field.
Triphala, a Thai herbal formulation, is reported to have immunomodulatory effects in mice.
However, it has not yet been investigated for immunostimulatory and side effects in healthy human volunteers.
Objective.
To evaluate the immunostimulatory and side effects of Triphala in a clinical phase I study.
Materials and Methods.
All volunteers took Triphala, 3 capsules per day for 2 weeks.
Complete physical examination, routine laboratory analysis, and immunological studies were performed before ingestion and after initial meeting for 4 consecutive weeks.
Results.
We found that Triphala demonstrated significant immunostimulatory effects on cytotoxic T cells (CD3−CD8+) and natural killer cells (CD16+CD56+).
Both of them increased significantly when compared with those of the control samples.
However, no significant change in cytokine secretion was detected.
All volunteers were healthy and showed no adverse effects throughout the duration of the study.
Conclusion.
Triphala has significant immunostimulatory effects on cellular immune response, especially cytotoxic T cells and natural killer cells.
Increases in the absolute number of these cells may provide a novel adjuvant therapy for HIV/AIDS positive people in terms of immunological improvement.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Phetkate, Pratya& Kummalue, Tanawan& U-pratya, Yaowalak& Kietinun, Somboon. 2012. Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028181
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Phetkate, Pratya…[et al.]. Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028181
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Phetkate, Pratya& Kummalue, Tanawan& U-pratya, Yaowalak& Kietinun, Somboon. Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028181
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028181
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر