Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities
المؤلفون المشاركون
Chen, Chuan
Chen, Hong
Chen, Weiqin
Wu, Shaohua
Lu, Yin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-24
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Endophytic fungi from the Chinese medicinal plant Actinidia macrosperma were isolated and identified for the first time.
This was the first study to evaluate their cytotoxic and antitumour activities against brine shrimp and five types of tumour cells, respectively.
In total, 17 fungal isolates were obtained.
Five different taxa were represented by 11 isolates, and six isolates were grouped into the species of Ascomycete Incertae sedis with limited morphological and molecular data.
Cytotoxic activity has been found in most isolates except AM05, AM06, and AM10.
The isolates AM07 (4.86 μg/mL), AM11 (7.71 μg/mL), and AM17 (14.88 μg/mL) exhibited significant toxicity against brine shrimp.
The results of the MTT assay to assess antitumour activity revealed that 82.4% of isolate fermentation broths displayed growth inhibition (50% inhibitory concentration IC50< 100 μg/mL).
Moreover, AM07, AM11, and AM17 showed strong antitumour activity in all the cell lines examined.
These results suggest that endophytic fungi in A.
macrosperma are valuable for the isolation and identification of novel cytotoxic and antitumour bioactive agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Yin& Chen, Chuan& Chen, Hong& Wu, Shaohua& Chen, Weiqin. 2011. Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028282
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Yin…[et al.]. Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1028282
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Yin& Chen, Chuan& Chen, Hong& Wu, Shaohua& Chen, Weiqin. Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028282
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028282
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر